PARP2 antibody

Principal name

PARP2 antibody

Alternative names for PARP2 antibody

PARP-2, ADPRT2, ADPRTL2, Poly [ADP-ribose] polymerase 2, PARP 2, EC=2.4.2.30, pADPRT-2, NAD(+) ADP-ribosyltransferase 2, Poly[ADP-ribose] synthetase 2

SwissProt ID

O50017 (Maize), O88554 (Mouse), Q11207 (Arath), Q9UGN5 (Human)

Gene ID

10038 (PARP2), 11546 (Parp2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP)

Background of PARP2 antibody

Poly(ADP-ribose) polymerase (PARP) is a highly conserved nuclear enzyme present in higher eukaryotes. This gene is a member of a family of enzymes that synthesize and transfer ADP-ribose polymers to protein to modify their functional properties. A key role of PARP in the cell is mediating the repair of single-strand DNA nicks. PARP-2 forms homodimers and hetero dimers with PARP-1 in the base excision repair (BER) pathway. To mediate repair PARP interacts with DNA and recruits DNA repair protein XRCC1, DNA ligase III, DNA polymerase beta and a kinase to the site of damage. As a marker for apoptosis, it has been shown that PARP cleavage mediated by caspase-3 activity occurs at the onset of apoptosis, and inhibition of PARP cleavage attenuates apoptosis in vitro.

General readings

Brunyanszki, A., et al. J. Invest. Dermatol. 130(11):2629-2637(2010)
Toller, I.M., et al. Cancer Res. 70(14):5912-5922(2010)
Nicolas, L., et al. Oncogene 29(19):2877-2883(2010)
Li, X., et al. J. Neurochem. 113(4):1012-1022(2010)
Quenet, D., et al. Exp. Cell Res. 315(16):2824-2834(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PARP2 antibody

TA303081 (1µg/ml) staining of Human Spleen Lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PARP2 antibody

Western blot analysis of extracts from K562 and HuvEc cells, using PARP2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PARP2 antibody

Host: Rabbit; Target Name: PARP2; Sample Tissue: MCF7 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PARP2 antibody

WB Suggested Anti-PARP2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Raji cell lysatePARP2 is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt ICC/IF, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PARP2 antibody

The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PARP2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT29G4 Purified Hu E, F, ICC/IF, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

PARP2 antibody

The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PARP2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT29G4 Purified Hu E, F, ICC/IF, WB
50 µl / €220.00
  Acris Antibodies GmbH

PARP2 (389-401) antibody

Human Adrenal (formalin-fixed, paraffin-embedded) stained with PARP2 antibody AP22537PU-N at 2.5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Eq, Hst, Hu, Mky, Ms, Por, Prim, Rb E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PARP2 (C-term) antibody

Western blot analysis of PARP2 Antibody (C-term) Cat.-No AP53164PU-N in mouse heart tissue lysates (35ug/lane). This demonstrates the PARP2 antibody detected the PARP2 protein (arrow). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PARP2 (N-term) antibody

Western blot analysis of PARP2 Antibody (N-term) Cat.-No AP53165PU-N in mouse heart tissue lysates (35ug/lane). This demonstrates the PARP2 antibody detected the PARP2 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PARP2 antibody

PARP2 polyclonal antibody ( Cat # PAB6953 ) ( 1 µg/ml ) staining of human spleen Lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

PARP2 antibody

PARP2 Rabbit Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

PARP2 antibody

Rat thyrocytes-FRTL-5; . Sample Type :. Rat thyrocytes-FRTL-5 . Primary Antibody Dilution :. 1:100 . Secondary Antibody :. Anti-rabbit-Texas Red . Secondary Antibody Dilution :. 1:100 . Color/Signal Descriptions :. Red: PARP2Blue: DAPI . Gene Name :. PARP2. Submitted by :. Syed A Morshed, Mount Sinai School of Medicine and James J Peters VA Medical Center; PARP2 antibody - middle region (ARP33758_P050) in Rat thyrocytes-FRTL-5 cells using Immunofluorescence Rabbit Aff - Purified Bov, Can, Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

PARP2 (402-414) antibody

Western blot using PARP2 antibody Goat Aff - Purified Hu E, WB
0.1 ml / €400.00
  Immuquest

PARP2 antibody

PARP2 Rabbit Aff - Purified Hu WB
0.1 ml / €320.00
  Novus Biologicals Inc.

PARP2 antibody

NB 100-2556 (1ug/ml) staining of HeLa Lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PARP2 antibody

Immunohistochemistry: PARP2 Antibody [NBP1-31498] - Immunohistochemical analysis of paraffin-embedded CA922, using NBP1-31498 at 1:100 dilution. Rabbit IgG Hu P
0.1 mg / €340.00
  Novus Biologicals Inc.

PARP2 antibody

Western Blot: PARP2 Antibody [NBP1-54680] - This Anti-PARP2 antibody was used in Western Blot of Raji tissue lysate at a concentration of 1.6ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PARP2 (233-583, His-tag)

PARP2 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PARP2 (233-583, His-tag)

PARP2 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

PARP2

PARP2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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