PAX2 antibody

Principal name

PAX2 antibody

Alternative names for PAX2 antibody

Pax-2, Paired box protein Pax-2

SwissProt ID

P32114 (Mouse), Q02962 (Human)

Gene ID

5076 (PAX2), 18504 (Pax2)

Available reactivities

Hu (Human), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PAX2 antibody

Pax proteins are a family of transcription factors with a highly conserved paired domain; many members also contain a paired-type homeodomain and/or an octapeptide. The transcriptional competence of a subfamily of Pax proteins is determined by a C-terminal regulatory module composed of activating and inhibitory sequences. At least 11 mammalian Pax genes are known and classified into four subgroups: Pax-1/9, Pax-2/5/8, Pax-3/7, and Pax-4/6. Most of these genes are involved in nervous system development. The homeobox, which encodes the DNA-binding homeo domain, is a DNA sequence motif conserved in many species; it has been used to identify many homologous genes involved in mammalian development. The paired box is another conserved sequence motif, first identified in the paired (prd) and gooseberry (gsb) Drosophila homeo domain genes. The amino-terminal region of the paired domain, including one of the three predicted alpha-helices, is necessary and sufficient for binding to DNA. Single amino acid substitution mutation in PAX1 causes formation of the mouse skeletal mutant undulated (un). Pax-2 is essential for development of neuronal tube, urogenital system, optic tracks and optic cups. Appropriate expression of PAX2 is essential for astrocyte differentiation and deficiency in eye is associated with coloboma with loss of astrocytes in the optic nerve, retina and abnormal path finding of the ganglion cells axons at the optic chiasm (2). Like other products of the PAX gene family, PAX2 encodes a conserved 128 amino acid paired box DNA-binding domain in the N-terminal portion of the molecule. The Anti-PAX selective antibodies were generated against conserved sequences at or near C-terminal end of the protein that is unique to specific PAX protein. The PAX1-selective antibodies are affinity purified against immobilized antigen based affinity chromatography which yielded epitope-specific antibodies. The PAX1 antibodies label a 29-32 kDa protein in Western blot using Western blot positive control for PAX1 (PC-PAX1). Anti-PAX1-selective antibodies are also available in affinity-purified form for confocal, Western blotting and immunocytochemical analyses.

General readings

General / background references:Muratovska A et al. Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival. Oncogene 22:7989-97 (2003). PubMed PMID: 12970747

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAX2 antibody

Western blot analysis of extracts of 231 cell lines, using PAX2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAX2 antibody

WB Suggested Anti- Antibody Titration: 1.0ug/ml; Positive Control: MCF-7 whole cell lysates Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PAX2 antibody

WB Suggested Anti-PAX2 Antibody Titration: 1.0ug/ml; ELISA Titer: 1:312500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAX2 antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 3C7 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PAX2 antibody

Western blot (WB) analysis of Pax-2 antibody (Cat.-No.: AP20670PU-N) in extracts from MCF7 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PAX2 antibody

PAX2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PAX2 antibody

Western Blot analysis of PAX2 expression in transfected 293T cell line (H00005076-T01) by PAX2 MaxPab polyclonal antibody.

Lane 1: PAX2 transfected lysate(47.41 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PAX2 antibody

Immunoperoxidase of monoclonal antibody to PAX2 on formalin-fixed paraffin-embedded human adrenal gland. [antibody concentration 0.5 ug/ml] Mouse IgG2a 3C7 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PAX2 antibody

PAX2 monoclonal antibody (M02), clone 2E4 Western Blot analysis of PAX2 expression in PC-12 ( Cat # L012V1 ). Mouse IgG2a 2E4 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PAX2 antibody

PAX2 Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

PAX2 antibody

Human Kidney; Rabbit Anti-PAX2 Antibody. Catalog Number: p100859. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; PAX2 antibody - middle region (P100859_P050) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

PAX2 antibody

Human Kidney; Rabbit Anti-PAX2 Antibody. Catalog Number: p100859. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; PAX2 antibody - middle region (P100859_T100) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

PAX2 antibody

Immunohistochemical analysis of PAX2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

PAX2 antibody

Immunohistochemical analysis of PAX2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

PAX2 antibody

Immunohistochemical analysis of PAX2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

PAX2 antibody

Paraffin Embedded Tissue: Human kidney Rabbit IgG Purified Hu P, WB
50 µg / €320.00
  Novus Biologicals Inc.

PAX2 antibody

Western Blot: Pax2 Antibody [NBP1-78131] - MCF7 cells (Lane 1) and PC-PAX2 (Lane 2). Apparnt MW of PAX2 in PC-PAX2 is 44kDa. Rabbit Aff - Purified Hu WB
0.2 ml / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PAX2 (transcript variant a)

PAX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PAX2 (transcript variant b)

PAX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PAX2 (transcript variant c)

PAX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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