PAX3 antibody

Principal name

PAX3 antibody

Alternative names for PAX3 antibody

Pax-3, HUP2, Paired box protein Pax-3

SwissProt ID

P23760 (Human), P24610 (Mouse)

Gene ID

5077 (PAX3), 18505 (Pax3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Ze (Zebrafish), Quail, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast), Gt (Goat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of PAX3 antibody

PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

General readings

1. Hsieh MJ, Yao YL, Lai IL, Yang WM.
Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1.
Biochem Biophys Res Commun. 2006 Oct 20;349(2):573-81.
PMID: 16945326
2. Dissanayake SK, Olkhanud PB, O'Connell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM, Weeraratna AT.
Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.
Cancer Res. 2008 Dec 15;68(24):10205-14.
PMID: 19074888

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 37 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAX3 antibody

  PAX3 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of A431 cell lines, using PAX3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAX3 antibody

AP31952PU-N PAX3 antibody staining of Mouse Brain lysate at 2 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PAX3 (N-term) antibody

  Goat Polyclonal Antibody against PAX3  
TA302938 (3µg/ml) staining of paraffin embedded Human Oesophagus. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. Goat Aff - Purified Bov, Hu, Ms, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAX3 (N-term) antibody

  Rabbit polyclonal PAX3 Antibody (N-term)  
PAX3 Antibody (N-term) (Cat. #TA324759) western blot analysis in A431 cell line lysates (35ug/lane).This demonstrates the PAX3 antibody detected the PAX3 protein (arrow). Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

PAX3 antibody

  Rabbit Polyclonal Anti-PAX3 Antibody  
Lanes: ; Lane1: 20ug RH30 lysate; Lane2: 20ug RH30 lysate; Lane3: 20ug RH41 lysate; Lane4: 20ug RH41 lysate; Primary Antibody Dilution: ; 1:1000; Secondary Antibody: ; Donkey anti-rabbit HRP; Secondary Antibody Dilution: ; 1:4000; Gene Name: ; PAX3; Submi Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

PAX3 antibody

  Rabbit Polyclonal Anti-PAX3 Antibody  
WB Suggested Anti-PAX3 Antibody Titration: 2.5ug/ml; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAX3 antibody

  Rabbit Polyclonal Anti-PAX3 Antibody  
WB Suggested Anti-PAX3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PAX3 (C-term) antibody

IHC Image of AM20561PU-N
Skeletal muscle, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a C2 Purified Hu, Quail P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PAX3 Control Peptide

PAX3
0.1 mg / €250.00
  Acris Antibodies GmbH

PAX3 antibody

PAX3 Rabbit Aff - Purified Hu E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PAX3 - human gene knockout kit via CRISPR

PAX3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAX3 - human gene knockout kit via CRISPR

PAX3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pax3 - mouse gene knockout kit via CRISPR

Pax3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pax3 - mouse gene knockout kit via CRISPR

Pax3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PAX3 (transcript variant PAX3)

  Purified recombinant protein of Homo sapiens paired box 3 (PAX3), transcript variant PAX3  
PAX3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PAX3 (N-term HIS tag, transcript variant PAX3D)

  Purified recombinant protein of Human paired box 3 (PAX3), transcript variant PAX3D, with N-terminal HIS tag, expressed in E.Coli, 50ug  
PAX3 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PAX3 overexpression lysate

PAX3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

PAX3 overexpression lysate

PAX3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

PAX3 overexpression lysate

PAX3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PAX3 overexpression lysate

PAX3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Items 1 to 20 of 37 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn