PAX6 antibody

Principal name

PAX6 antibody

Alternative names for PAX6 antibody

Pax-6, Aniridia type II protein, AN2, Oculorhombin, Paired box protein Pax-6

SwissProt ID

O18381 (Drome), P26367 (Human), P26630 (Danre), P47237 (Chick), P55864 (Xenla), P63015 (Mouse), P63016 (Rat), Q1LZF1 (Bovin)

Gene ID

5080 (PAX6), 18508 (Pax6), 25509

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C)

Background of PAX6 antibody

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells .PAX6 is the most researched of the PAX genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.

General readings

Kim,E.A., et al., (2006) J. Biol. Chem. 281 (11), 7489-7497

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAX6 antibody

  Goat Polyclonal Antibody against PAX6  
TA303232 (0.5µg/ml) staining of Mouse Eye lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAX6 antibody

  Rabbit polyclonal anti-PAX6 antibody  
Western blot analysis of PAX6 with rat kidney tissue lysate. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PAX6 antibody

  Rabbit Polyclonal Anti-PAX6 Antibody  
WB Suggested Anti-PAX6 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PAX6 antibody

  Rabbit Polyclonal Anti-PAX6 Antibody  
WB Suggested Anti-PAX6 Antibody Titration: 0.0625 ug/ml; ELISA Titer: 1: 12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PAX6 antibody

Western blot analysis using PAX6 mAb against human PAX6 (AA: 1-223) recombinant protein. (Expected MW is 50 kDa) Mouse IgG1 1C8 Ascites Hu E, F, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

PAX6 antibody

Western blot analysis of PAX6 in human cerebellum lysate using PAX6 Antibody Cat.-No AM50305PU-N (Clone PAX6/498). Mouse IgG1 PAX6/496 Purified Chk, Hu, Ms, Rt C, F, ICC/IF, IP, WB
0.2 mg / €410.00
  Acris Antibodies GmbH

PAX6 antibody

Western blot analysis of PAX6 in human cerebellum lysate using PAX6 Antibody Cat.-No AM50305PU-N (Clone PAX6/498). Mouse IgG1 PAX6/496 Purified Chk, Hu, Ms, Rt C, F, ICC/IF, IP, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

PAX6 antibody

Western blot analysis of PAX6 in human cerebellum lysate using PAX6 Antibody Cat.-No AM50305PU-N (Clone PAX6/498). Mouse IgG1 PAX6/496 Purified Chk, Hu, Ms, Rt C, F, ICC/IF, IP, WB
20 µg / €180.00
  Acris Antibodies GmbH

PAX6 (Center) antibody

Western blot analysis of PAX6 Antibody (Center) (AP17622PU-N) in Hela cell line lysates (35ug/lane). PAX6 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PAX6 antibody

PAX6 Antibody (Cat. #AP53180PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAX6 Antibody for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, P ICC/IF, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PAX6 antibody

PAX6 Rabbit Purified Hu, Ms, Rt, Xen, Ze E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PAX6 - human gene knockout kit via CRISPR

PAX6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PAX6 - human gene knockout kit via CRISPR

PAX6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pax6 - mouse gene knockout kit via CRISPR

Pax6 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pax6 - mouse gene knockout kit via CRISPR

Pax6 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pax6 - mouse gene knockout kit via CRISPR

Pax6 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pax6 - mouse gene knockout kit via CRISPR

Pax6 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PAX6 (full length, N-term HIS tag, transcript variant 2)

  Purified recombinant protein of Human paired box 6 (PAX6), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
PAX6 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PAX6 (mGFP-tagged) - Human paired box 6 (PAX6), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PAX6 (mGFP-tagged) - Human paired box 6 (PAX6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PAX6 (mGFP-tagged) - Human paired box 6 (PAX6), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PAX6 (mGFP-tagged) - Human paired box 6 (PAX6), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.

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