PBRM1 / PB1 antibody

Principal name

PBRM1 / PB1 antibody

Alternative names for PBRM1 / PB1 antibody

Protein polybromo-1, polybromo 1, Polybromo-1D, BAF180, BRG1-associated factor 180

SwissProt ID

P80964 (Pig), Q86U86 (Human), Q86U86-4, Q8BSQ9 (Mouse), Q90941 (Chick), Q9H2T4 (Human)

Gene ID

55193 (PBRM1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of PBRM1 / PB1 antibody

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PB1/BAF180 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PB1/BAF180 has been proposed to function as a tumor suppressor protein. Recently, PB1/BAF180 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21. Alternate names for PB1/BAF180 include protein polybromo-1, polybromo-1D, BRG1-associated factor 180, hPB1, and PBRM1.

General readings

Xia,W., (2008) Cancer Res. 68 (6), 1667-1674

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PBRM1 / PB1 antibody

WB Suggested Anti-PBRM1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PBRM1 / PB1 antibody

Hum. Fetal Brain; Host: Rabbit; Target Name: NOP56; Sample Tissue: Human Fetal Brain; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PBRM1 / PB1 antibody

Western Blot analysis of PBRM1 expression in transfected 293T cell line (H00055193-T01) by PBRM1 MaxPab polyclonal antibody.

Lane 1: PB1 transfected lysate(33.77 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PBRM1 / PB1 antibody

Immunofluorescence of purified MaxPab antibody to PB1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

PBRM1 / PB1 antibody

PBRM1 / PB1 Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PBRM1 / PB1 (N-term) antibody

PBRM1 / PB1 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PBRM1 / PB1 antibody

Hum. Fetal Brain; Host: Rabbit. Target Name: NOP56 . Sample Tissue: Human Fetal Brain . Antibody Dilution: 1.0ug/ml.; PBRM1 antibody - middle region (ARP39332_P050) in Hum. Fetal Brain cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

PBRM1 / PB1 antibody

Western Blot: PB1 Antibody [NB100-79832] - Detection of Human PB1/BAF180 by Western Blot of  Immunoprecipitate. Samples: Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells. Antibodies: Affinity purified  rabbit anti-PB1/BAF180 antibody NB100-79832 used for IP at 3  mcg/mg lysate.   Detection: Chemiluminescence with an exposure time 10  seconds. Rabbit IgG Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

PBRM1 / PB1 antibody

Western Blot and  Immunoprecipitation: PB1 Antibody [NB100-79833] - Detection of Human and Mouse PB1/BAF180 on HeLa whole cell lysate using NB100-79833. PB1/BAF180 was immunoprecipitated by rabbit anti-PB1/BAF180 antibody NB100-79832. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €440.00
  Novus Biologicals Inc.

PBRM1 / PB1 antibody

Western Blot:polybromo 1 Antibody   [NBP1-32025]- (30 ug of whole cell lysate) A: A431 5% SDS PAGE PB1 antibody  diluted at 1:500 Rabbit IgG Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

PBRM1 / PB1 antibody

Immunohistochemistry-Paraffin: polybromo 1 Antibody [NBP1-90016] - Immunohistochemical staining of human cerebral cortex shows strong nuclear positivity in neuronal cells. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PBRM1 / PB1

PBRM1 / PB1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PBRM1 / PB1

PBRM1 / PB1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PB1 293T Cell Transient Overexpression Lysate(Denatured)

PB1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

PB1 293T Cell Transient Overexpression Lysate(Denatured)

PB1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

15 Item(s)

per page
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