PCBP2 / hnRNP-E2 antibody

Principal name

PCBP2 / hnRNP-E2 antibody

Alternative names for PCBP2 / hnRNP-E2 antibody

Poly(rC)-binding protein 2, Alpha-CP2, Heterogeneous nuclear ribonucleoprotein E2

SwissProt ID

Q15366 (Human), Q61990 (Mouse)

Gene ID

5094 (PCBP2), 18521 (Pcbp2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Chk (Chicken), Por (Porcine), Rb (Rabbit), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of PCBP2 / hnRNP-E2 antibody

PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5\'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes.The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5\'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.

General readings

Oh,J.H., (2005) Mamm. Genome 16 (12), 942-954

  1. Quick-Filters:
  2. Cited (1)
  3. Highly Validated (2)

Items 1 to 20 of 44 total

per page
Page:
  1. 1
  2. 2
  3. 3

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCBP2 / hnRNP-E2 antibody

  Rabbit Polyclonal antibody to PCBP2 (poly(rC) binding protein 2)  
Sample (50 ug of whole cell lysate). A: mouse liver. 10% SDS PAGE. TA308051 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 5F12 Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PCBP2 / hnRNP-E2 antibody

  Rabbit polyclonal antibody to PCBP2 (poly(rC) binding protein 2)  
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. TA308000 diluted at 1:500 Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 antibody

  PCBP2 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using PCBP2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 antibody

  Rabbit Polyclonal Anti-PCBP2 Antibody  
WB Suggested Anti-PCBP2 Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate; PCBP2 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 antibody

  Rabbit Polyclonal Anti-PCBP2 Antibody  
WB Suggested Anti-PCBP2 Antibody Titration: 1.25 ug/ml; Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that PCBP2 is expressed in Jurkat Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PCBP2 - human gene knockout kit via CRISPR

PCBP2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PCBP2 - human gene knockout kit via CRISPR

PCBP2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCBP2 - human gene knockout kit via CRISPR

PCBP2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCBP2 - human gene knockout kit via CRISPR

PCBP2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pcbp2 - mouse gene knockout kit via CRISPR

Pcbp2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pcbp2 - mouse gene knockout kit via CRISPR

Pcbp2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PCBP2 / hnRNP-E2 (transcript variant 1)

  Recombinant protein of human poly(rC) binding protein 2 (PCBP2), transcript variant 1  
PCBP2 / hnRNP-E2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 (transcript variant 2)

  Recombinant protein of human poly(rC) binding protein 2 (PCBP2), transcript variant 2  
PCBP2 / hnRNP-E2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 (transcript variant 3)

  Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 3  
PCBP2 / hnRNP-E2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 (transcript variant 7)

  Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 7  
PCBP2 / hnRNP-E2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PCBP2 / hnRNP-E2 (transcript variant 6)

  Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 6  
PCBP2 / hnRNP-E2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PCBP2 overexpression lysate

PCBP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PCBP2 overexpression lysate

PCBP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PCBP2 overexpression lysate

PCBP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Items 1 to 20 of 44 total

per page
Page:
  1. 1
  2. 2
  3. 3
  • LinkedIn