PCDHA12 antibody

Principal name

PCDHA12 antibody

Alternative names for PCDHA12 antibody

Protocadherin alpha-12, PCDH-alpha-12

SwissProt ID

Q9UN75 (Human)

Gene ID

56137 (PCDHA12)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of PCDHA12 antibody

PCDHA12 is a potential calcium-dependent cell-adhesion protein. PCDHA12 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

General readings

Schmutz,J., (2004) Nature 431 (7006), 268-274

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHA12 antibody

  Rabbit polyclonal Anti-PCDHA12 Antibody  
WB Suggested Anti-PCDHA12 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PCDHA12 - human gene knockout kit via CRISPR

PCDHA12 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PCDHA12 - human gene knockout kit via CRISPR

PCDHA12 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHA12 - human gene knockout kit via CRISPR

PCDHA12 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHA12 - human gene knockout kit via CRISPR

PCDHA12 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PCDHA12 (mGFP-tagged)-Human protocadherin alpha 12 (PCDHA12), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHA12 (mGFP-tagged)-Human protocadherin alpha 12 (PCDHA12), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCDHA12 (Myc-DDK-tagged)-Human protocadherin alpha 12 (PCDHA12), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHA12 (Myc-DDK-tagged)-Human protocadherin alpha 12 (PCDHA12), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

7 Item(s)

per page
  • LinkedIn