PCDHA8 antibody

Principal name

PCDHA8 antibody

Alternative names for PCDHA8 antibody

Protocadherin alpha-8, PCDH-alpha-8

SwissProt ID

Q9Y5H6 (Human)

Gene ID

56140 (PCDHA8)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PCDHA8 antibody

The PCDHA8 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

General readings

Wu, C., et al. Proteomics 7(11):1775-1785 (2007)
Wu, Q., et al. Genome Res. 11(3):389-404 (2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572 (2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180 (2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129 (2000)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHA8 (C-term) antibody

PCDHA8 Antibody (C-term) (Cat. #TA324458) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PCDHA8 antibody detected the PCDHA8 protein (arrow). Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

PCDHA8 antibody

Western Blot analysis of PCDHA8 expression in transfected 293T cell line (H00056140-T01) by PCDHA8 MaxPab polyclonal antibody.

Lane 1: PCDHA8 transfected lysate(89.54 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PCDHA8 antibody

Immunohistochemistry-Paraffin: PCDHA8 Antibody [NBP1-86195] Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PCDHA8

PCDHA8 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PCDHA8

PCDHA8 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PCDHA8 293T Cell Transient Overexpression Lysate(Denatured)

PCDHA8 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

PCDHA8 overexpression lysate

PCDHA8 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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