PCDHAC2 antibody

Principal name

PCDHAC2 antibody

Alternative names for PCDHAC2 antibody

Protocadherin alpha-C2, PCDH-alpha-C2

SwissProt ID

Q9Y5I4 (Human)

Gene ID

56134 (PCDHAC2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PCDHAC2 antibody

PCDHAC2 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

General readings

Wu, Q., et al. Genome Res. 11(3):389-404 (2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572 (2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180 (2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129 (2000)
Sugino, H., et al. Genomics 63(1):75-87 (2000)

10 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHAC2 antibody

  Rabbit polyclonal Anti-PCDHAC2 Antibody  
WB Suggested Anti-PCDHAC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PCDHAC2 (Center) antibody

Immunohistochemistry analysis in human brain tissue (formalin-fixed, paraffin-embedded) using PCDHAC2 antibody Cat.-No.AP53204PU-N, followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of PCDHAC2 antibody for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PCDHAC2 - human gene knockout kit via CRISPR

PCDHAC2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHAC2 - human gene knockout kit via CRISPR

PCDHAC2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHAC2 - human gene knockout kit via CRISPR

PCDHAC2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PCDHAC2 overexpression lysate

PCDHAC2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PCDHAC2 (mGFP-tagged)-Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHAC2 (mGFP-tagged)-Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCDHAC2 (mGFP-tagged) - Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHAC2 (mGFP-tagged) - Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,850.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCDHAC2 (Myc-DDK-tagged)-Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHAC2 (Myc-DDK-tagged)-Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCDHAC2 (Myc-DDK tagged) - Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHAC2 (Myc-DDK tagged) - Human protocadherin alpha subfamily C, 2 (PCDHAC2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,670.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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