PCDHB12 antibody

Principal name

PCDHB12 antibody

Alternative names for PCDHB12 antibody

Protocadherin beta-12, PCDH-beta-12

SwissProt ID

Q9Y5F1 (Human)

Gene ID

56124 (PCDHB12)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PCDHB12 antibody

The PCDHB12 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

General readings

Vanhalst, K., et al. FEBS Lett. 495 (1-2), 120-125 (2001)
Wu, Q., et al. Genome Res. 11(3):389-404 (2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572 (2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180 (2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129 (2000)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHB12 (C-term) antibody

Immunohistochemistry analysis in human brain tissue (formalin-fixed, paraffin-embedded) using PCDHB12 antibody Cat.-No. AP53207PU-N (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PCDHB12 antibdy for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PCDHB12 antibody

PCDHB12 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PCDHB12 antibody

Detection limit for recombinant GST tagged PCDHB12 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2a 1D11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PCDHB12 (full length, N-term HIS tag)

PCDHB12 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

PCDHB12

PCDHB12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PCDHB12

PCDHB12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

PCDHB12

PCDHB12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PCDHB12

PCDHB12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PCDHB12 overexpression lysate

PCDHB12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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