PCDHB12 antibody

Principal name

PCDHB12 antibody

Alternative names for PCDHB12 antibody

Protocadherin beta-12, PCDH-beta-12

SwissProt ID

Q9Y5F1 (Human)

Gene ID

56124 (PCDHB12)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PCDHB12 antibody

The PCDHB12 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

General readings

Vanhalst, K., et al. FEBS Lett. 495 (1-2), 120-125 (2001)
Wu, Q., et al. Genome Res. 11(3):389-404 (2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572 (2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180 (2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129 (2000)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHB12 (C-term) antibody

Immunohistochemistry analysis in human brain tissue (formalin-fixed, paraffin-embedded) using PCDHB12 antibody Cat.-No. AP53207PU-N (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PCDHB12 antibdy for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PCDHB12 (full length, N-term HIS tag)

  Purified recombinant protein of Human protocadherin beta 12 (PCDHB12), full length, with N-terminal HIS tag, expressed in E. coli, 50ug  
PCDHB12 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PCDHB12 overexpression lysate

PCDHB12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PCDHB12 (mGFP-tagged) - Human protocadherin beta 12 (PCDHB12), 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHB12 (mGFP-tagged) - Human protocadherin beta 12 (PCDHB12), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCDHB12 (Myc-DDK tagged) - Human protocadherin beta 12 (PCDHB12) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHB12 (Myc-DDK tagged) - Human protocadherin beta 12 (PCDHB12) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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