PCDHB13 antibody

Principal name

PCDHB13 antibody

Alternative names for PCDHB13 antibody

Protocadherin beta-13, PCDH-beta-13

SwissProt ID

Q9Y5F0 (Human)

Gene ID

56123 (PCDHB13), 6156123 (araA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of PCDHB13 antibody

PCDHB13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

General readings

Clark, H.F., et al. Genome Res. 13(10):2265-2270 (2003)
Frank, M., et al. Curr. Opin. Cell Biol. 14(5):557-562 (2002)
Vanhalst, K., et al. FEBS Lett. 495 (1-2), 120-125 (2001)
Wu, Q., et al. Genome Res. 11(3):389-404 (2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572 (2000)

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHB13 antibody

  Rabbit polyclonal Anti-PCDHB13 Antibody  
WB Suggested Anti-PCDHB13 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PCDHB13 (Center) antibody

Western blot analysis in MDA-MB435 cell line lysates (35ug/lane) using PCDHB13 antibody Cat.-No. AP53208PU-N. This demonstrates the PCDHB13 antibody detected the PCDHB13 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PCDHB13 - human gene knockout kit via CRISPR

PCDHB13 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PCDHB13 - human gene knockout kit via CRISPR

PCDHB13 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHB13 - human gene knockout kit via CRISPR

PCDHB13 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHB13 - human gene knockout kit via CRISPR

PCDHB13 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PCDHB13 overexpression lysate

PCDHB13 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PCDHB13 (mGFP-tagged)-Human protocadherin beta 13 (PCDHB13), 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHB13 (mGFP-tagged)-Human protocadherin beta 13 (PCDHB13), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCDHB13 (Myc-DDK-tagged)-Human protocadherin beta 13 (PCDHB13), 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHB13 (Myc-DDK-tagged)-Human protocadherin beta 13 (PCDHB13), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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