PCDHGA1 antibody
Principal name
PCDHGA1 antibody
Alternative names for PCDHGA1 antibody
Protocadherin gamma-A1, PCDH-gamma-A1
SwissProt ID
Q9Y5H4 (Human)
Gene ID
56114 (PCDHGA1)
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of PCDHGA1 antibody
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
General readings
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Wu, Q., et al. Genome Res. 11(3):389-404(2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129(2000)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP53213PU-N | PCDHGA1 (Center) antibody |
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 |
Rabbit | Ig | Aff - Purified | Hu | P, WB |
0.4 ml /
€370.00
|
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC217748L2V | Lenti ORF particles, PCDHGA1 (mGFP-tagged)-Human protocadherin gamma subfamily A, 1 (PCDHGA1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€1,988.00
|
|
| OriGene Technologies, Inc. | ||
| RC217748L1V | Lenti ORF particles, PCDHGA1 (Myc-DDK-tagged)-Human protocadherin gamma subfamily A, 1 (PCDHGA1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,793.00
|
|
| OriGene Technologies, Inc. | ||
