PCDHGA8 antibody

Principal name

PCDHGA8 antibody

Alternative names for PCDHGA8 antibody

Protocadherin gamma-A8, PCDH-gamma-A8, KIAA0327

SwissProt ID

Q9Y5G5 (Human)

Gene ID

9708 (PCDHGA8)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PCDHGA8 antibody

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

General readings

Wu, Q., et al. Genome Res. 11(3):389-404(2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129(2000)
Wu, Q., et al. Cell 97(6):779-790(1999)

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHGA8 (C-term) antibody

  Rabbit polyclonal PCDHGA8 Antibody (C-term)  
PCDHGA8 Antibody (C-term) (Cat. #TA324456) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PCDHGA8 antibody detected the PCDHGA8 protein (arrow). Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PCDHGA8 - human gene knockout kit via CRISPR

PCDHGA8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PCDHGA8 - human gene knockout kit via CRISPR

PCDHGA8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHGA8 - human gene knockout kit via CRISPR

PCDHGA8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PCDHGA8 - human gene knockout kit via CRISPR

PCDHGA8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PCDHGA8 overexpression lysate

PCDHGA8 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PCDHGA8 (mGFP-tagged) - Human protocadherin gamma subfamily A, 8 (PCDHGA8), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHGA8 (mGFP-tagged) - Human protocadherin gamma subfamily A, 8 (PCDHGA8), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,930.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCDHGA8 (Myc-DDK tagged) - Human protocadherin gamma subfamily A, 8 (PCDHGA8), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PCDHGA8 (Myc-DDK tagged) - Human protocadherin gamma subfamily A, 8 (PCDHGA8), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,740.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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