PCDHGC3 antibody

Principal name

PCDHGC3 antibody

Alternative names for PCDHGC3 antibody

Protocadherin gamma-C3, PCDH-gamma-C3, Protocadherin-2, Protocadherin 2, PCDH2, Protocadherin-43, Protocadherin 43, PC-43, PC43

SwissProt ID

Q91XX1, Q9UN70 (Human), Q9UN70-2

Gene ID

5098 (PCDHGC3), 93706

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PCDHGC3 antibody

The PCDHGC3 gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. PCDHGC3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain. This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five.
These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

General readings

Reiss, K., et al. J. Biol. Chem. 281(31):21735-21744 (2006)
Wu, Q., et al. Genome Res. 11(3):389-404 (2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572 (2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180 (2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129 (2000)

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCDHGC3 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Gammaprotocadherin-C3 and –A3 and untagged Kv2.1 plasmids and probed with N174B/27 (left) and N159/5 (right) TC supe. Mouse IgG1 N174B/27 Supernatant Ms ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

PCDHGC3 antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Gammaprotocadherin-C3 and –A3 and untagged Kv2.1 plasmids and probed with N174B/27 (left) and N159/5 (right) TC supe. Mouse IgG1 N174B/27 Purified Ms ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

PCDHGC3 (720-804, Cytopl. Dom.) antibody

PCDHGC3 Mouse IgG1 S174B-27 Purified Ms ICC/IF, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

PCDHGC3 (Center) antibody

Immunohistochemistry analysis human brain tissue (Formalin-fixed, Paraffin-embedded) using PCDHGC3 antibody Cat.-No. AP53216PU-N, followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PCDHGC3 antibody for IHC; Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PCDHGC3 antibody

PCDHGC3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PCDHGC3 antibody

PCDHGC3 Mouse IgG2a 3F10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PCDHGC3 antibody

Detection limit for recombinant GST tagged PCDHGC3 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2a 3A1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PCDHGC3 antibody

PCDHGC3 Mouse IgG2a 4F6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PCDHGC3 antibody

PCDHGC3 Mouse IgG2a 1E7 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

PCDHGC3 antibody

PCDHGC3 monoclonal antibody (M07), clone 1C4. Western Blot analysis of PCDHGC3 expression in Jurkat ( Cat # L017V1 ). Mouse IgG2a 1C4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PCDHGC3 antibody

Human 721_B; WB Suggested Anti-PCDHGC3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: 721_B cell lysate. There is BioGPS gene expression data showing that PCDHGC3 is expressed in 721_B.; PCDHGC3 antibody - N-terminal region (ARP45334_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

PCDHGC3 antibody

Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; PCDHGC3 antibody - C-terminal region (ARP45336_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PCDHGC3 antibody

Western Blot: PCDHGC3 Antibody [NBP1-59233] - This Anti-PCDHGC3 antibody was used in Western Blot of 721_B tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

PCDHGC3 antibody

Western Blot: PCDHGC3 Antibody [NBP1-59239] - This Anti-PCDHGC3 antibody was used in Western Blot of 721_B tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PCDHGC3

PCDHGC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PCDHGC3

PCDHGC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

PCDHGC3

PCDHGC3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PCDHGC3

PCDHGC3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

18 Item(s)

per page
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