PCMT1 / PIMT antibody

Principal name

PCMT1 / PIMT antibody

Alternative names for PCMT1 / PIMT antibody

Protein-L-isoaspartate(D-aspartate) O-methyltransferase, Protein-beta-aspartate methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, L-isoaspartyl protein carboxyl methyltransferase

SwissProt ID

P15246 (Bovin), P22061 (Human), P22062 (Rat), P23506 (Mouse), P80895 (Pig), Q27869 (Drome), Q27873 (Caeel), Q99625 (Human)

Gene ID

5110 (PCMT1), 25604 (Pcmt1)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PCMT1 / PIMT antibody

Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Kosugi,S., (2008) Biochem. Biophys. Res. Commun. 371 (1), 22-27

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PCMT1 / PIMT antibody

  Rabbit Polyclonal antibody to PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase)  
Sample (30 ug of whole cell lysate). A: 293T. 12% SDS PAGE. TA308667 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PCMT1 / PIMT antibody

  Rabbit Polyclonal Anti-PCMT1 Antibody  
WB Suggested Anti-PCMT1 Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysatePCMT1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PCMT1 / PIMT

  Recombinant protein of human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1)  
PCMT1 / PIMT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PCMT1 / PIMT (1-227, His-tag)

PCMT1 / PIMT Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €670.00
  Acris Antibodies GmbH

PCMT1 / PIMT (1-227, His-tag)

PCMT1 / PIMT Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €250.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PCMT1 (mGFP-tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1), 200 uL, >10^7 TU/mL

Lenti ORF particles, PCMT1 (mGFP-tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCMT1 (mGFP-tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1), 200 uL, >10^7 TU/mL

Lenti ORF particles, PCMT1 (mGFP-tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCMT1 (Myc-DDK tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PCMT1 (Myc-DDK tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, PCMT1 (Myc-DDK tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PCMT1 (Myc-DDK tagged) - Human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pcmt1 (GFP-tagged ORF) - Rat protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 (Pcmt1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pcmt1 (GFP-tagged ORF) - Rat protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 (Pcmt1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

10 Item(s)

per page
  • LinkedIn