PDCL3 antibody

Principal name

PDCL3 antibody

Alternative names for PDCL3 antibody

Phosducin-like protein 3, VIAF1, VIAF-1, HTPHLP, PhPL3, Viral IAP-associated factor 1

SwissProt ID

Q0VCW8 (Bovin), Q4KLJ8 (Rat), Q6P268 (Danre), Q8BVF2 (Mouse), Q9H2J4 (Human)

Gene ID

79031 (PDCL3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PDCL3 antibody

PDCL3 (phosducin-like 3), also known as VIAF1 (viral IAP-associated factor 1), VIAF, PHLP3 or HTPHLP, is a widely expressed protein that belongs to the phosducin-like family of proteins. phosducin-like family members associate with the cytosolic chaperonin complex (CCT) and regulate the folding of proteins. Localizing to the cytoplasm, PDCL3 does not appear to play a role in G protein signaling, but participates in the chaperone-assisted folding of proteins, such as beta Tubulin and Actin, that are involved in the regulation of cell cycle progression. More specifically, PDCL3, when associated with CCT, represses the ATPase activity of CCT and ultimately disrupts the folding of the Actin or tubulin substrates.

General readings

Wilkinson J.C., et al. (2004) Biol. Chem. 279(49):51091-51099Hillier L.W., et al. (2005) Nature 434(7034):724-731

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PDCL3 antibody

Western blot analysis of PDCL3 in human brain tissue lysate with PDCL3 antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PDCL3 antibody

Fig. 1: The extract of Jurkat (40ug), A549(40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Fig. 2: The Human Recombinant protein PDCL3(100ng) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 AT8F9 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

PDCL3 antibody

Fig. 1: The extract of Jurkat (40ug), A549(40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Fig. 2: The Human Recombinant protein PDCL3(100ng) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDCL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 AT8F9 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

PDCL3 antibody

PDCL3 monoclonal antibody (M01), clone 1F10 Western Blot analysis of PDCL3 expression in Jurkat ( Cat # L017V1 ). Mouse IgG1 1F10 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PDCL3 antibody

PDCL3 monoclonal antibody (M01), clone 1F10 Western Blot analysis of PDCL3 expression in Jurkat ( Cat # L017V1 ). Mouse IgG1 1F10 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

PDCL3 antibody

PDCL3 Mouse IgG1 2D7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PDCL3 antibody

Immunohistochemistry-Paraffin: PDCL3 Antibody [NBP1-80626] - Immunohistochemical staining of human rectum shows moderate nuclear and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

PDCL3 antibody

Immunohistochemistry-Paraffin: PDCL3 Antibody [NBP1-80627] - Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PDCL3

PDCL3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PDCL3 (1-239, His-tag)

PDCL3 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

PDCL3 (1-239, His-tag)

PDCL3 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

PDCL3

PDCL3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PDCL3

PDCL3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PDCL3 overexpression lysate

PDCL3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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