PDE2A antibody

Principal name

PDE2A antibody

Alternative names for PDE2A antibody

CGS-PDE, cGSPDE, cGMP-dependent 3',5'-cyclic phosphodiesterase, Cyclic GMP-stimulated phosphodiesterase

SwissProt ID

O00408 (Human), P14099 (Bovin), Q01062 (Rat), Q922S4 (Mouse)

Gene ID

5138 (PDE2A), 81743 (Pde2a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PDE2A antibody

Cyclic nucleotides are important intracellular second messengers which play important role variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. One of the many phosphodiesterases that compartmentalized and hydrolyze cAMP and cGMP in to AMP and GMP respectively are phosphodiesterase type 2 There are two member of PDE2A gene are cloned and designated as PD2A and PDE2B (Rascon et. al., 2002). Each of the PDE2A and PDE2B genes are 2793 Bases and 930 amino acids with an apparent MW of 100 kDA. The catalytic domain of PDE2A is homologous to all other 11 PDE family members. The PDE2A has specificity for cAMP with Km of 2.4 uM and its activity is modulated by the presence of cGMP. In contrast, the PDE2B does not hydrolyze cGMP nor its activity is altered by the presence of cGMP. Western blot analyses of PDE2A reveals a variety of tissues including neocortex, cerebellum, heart, kidney lungs, pulmonary artery and skeletal muscle (Sadhu et. al., 2002). The PDE2A expression was evident in venous arterial endothelial cells but not in arterial endothelial cells (Sadhu et. al., 1999). The PDE2A expression was also noted in corpus cavernosum along with a wide repertoire of other PDEs enzymes (Kuthe et. al., 1999).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI1G9 (formerly 1G9)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-PDE2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502320) Mouse IgG1 OTI1G9 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI4H8 (formerly 4H8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE2A (RC207219, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE2A. Mouse IgG1 OTI4H8 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI3A4 (formerly 3A4)  
Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-PDE2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502389) Mouse IgG2b OTI3A4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI4D10 (formerly 4D10)  
Anti-PDE2A mouse monoclonal antibody (TA502683) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE2A(RC207219). Mouse IgG2a OTI4D10 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A (N-term) antibody

  Rabbit Polyclonal Anti-PDE2A Antibody (N-Terminus)  
Anti-PDE2A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

PDE2A antibody

  Rabbit polyclonal Anti-Pde2a Antibody  
WB Suggested Anti-Pde2a Antibody; Titration: 1.0 ug/ml; Positive Control: Rat Brain Rabbit IgG Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI5D9 (formerly 5D9)  
Western blot analysis of extracts (10ug) from 5 different cell lines by using anti-PDE2A monoclonal antibody. (1:200) Mouse IgG1 OTI5D9 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI5B10 (formerly 5B10)  
Anti-PDE2A mouse monoclonal antibody (TA502319) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE2A(RC207219). Mouse IgG2a OTI5B10 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI2A5 (formerly 2A5)  
Anti-PDE2A mouse monoclonal antibody (TA502349) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE2A(RC207219). Mouse IgG1 OTI2A5 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI4D2 (formerly 4D2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE2A (RC207219, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE2A. Mouse IgG2a OTI4D2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

  PDE2A mouse monoclonal antibody, clone OTI2F1 (formerly 2F1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE2A (RC207219, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE2A. Mouse IgG1 OTI2F1 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDE2A antibody

Western blot using AP00652SU-N (1:20,000) against lysate from COS cells transfected with the indicated human PDE isoform. Rabbit Serum Hu, Ms, Rt C, IP, WB
0.1 ml / €420.00
  Acris Antibodies GmbH

PDE2A Control Peptide

PDE2A
0.25 mg / €250.00
  Acris Antibodies GmbH

PDE2A (C-term) antibody

Immunostaining of PDE2A expressing cells with AP10205PU-N (1:250). Rabbit Aff - Purified Hu, Ms, Rt IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

PDE2A antibody

PDE2A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PDE2A antibody

PDE2A monoclonal antibody (M01), clone 4F4 Western Blot analysis of PDE2A expression in IMR-32 ( Cat # L008V1 ). Mouse IgG2a 4F4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PDE2A (N-term) antibody

Rat Brain; WB Suggested Anti-Pde2a Antibody. . Titration: 1.0 ug/ml. . Positive Control: Rat Brain; Pde2a antibody - N-terminal region (ARP56379_P050) in Rat Brain cells using Western Blot Rabbit Aff - Purified Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

PDE2A - human gene knockout kit via CRISPR

PDE2A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PDE2A - human gene knockout kit via CRISPR

PDE2A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PDE2A - human gene knockout kit via CRISPR

PDE2A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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