PDE9A antibody

Principal name

PDE9A antibody

Alternative names for PDE9A antibody

Phosphodiesterase 9A, Phosphodiesterase PDE9A21, HSPDE9A2, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

SwissProt ID

O70628 (Mouse), O76083 (Human), Q86WN8 (Human)

Gene ID

5152 (PDE9A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Ze (Zebrafish), Bt (Bat), Chk (Chicken), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PDE9A antibody

Cyclic nucleotide phosphodiesterases (PDEs) are enzymes which catalyzes the hydrolysis of cyclic adenosine 30,50-monophosphate (cAMP) and/or cyclic guanosine 30,50-monophosphate (cGMP); and PDE9A (high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) is a PDE member which hydrolyzes the second messenger cGMP, an important regulator of several critical cellular physiological processes. PDE9A activity gets modulated by metal ions and it can bind 2 divalent metal cations per subunit - site 1 binds zinc ions, whereas, site 2 preferentially associates with magnesium and/or manganese ions. PDE9A is expressed in most of the solid tissues and because of its location as well as contribution to the regulation of steady-state cellular concentrations of cyclic nucleotides, PDE9A has been suggested as a potential candidate for diseases such as bipolar affective disorder and its overexpression has been linked to Down syndrome. Moreover, PDE9A deficient mice fed a high-fat diet have been reported to exhibit a reduced weight gain and fat mass compared with wild-type mice.

General readings

Huai,Q., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (26), 9624-9629

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 46 total

per page
Page:
  1. 1
  2. 2
  3. 3

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PDE9A antibody

Human kidney; PDE9A Antibody (ARP45760_P050) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Rt, Ze P, WB
50 µg / €350.00
  AVIVA Systems Biology

PDE9A antibody

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308688 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PDE9A antibody

Western Blot: PDE9A Antibody [TA336701] - WB analysis of PDE9A in HeLa whole cell lysate. Rabbit Purified Hu, Ms, Rt C, ICC/IF, IP, P, WB
50 µl / €325.00
  OriGene Technologies, Inc.

PDE9A antibody

Anti-PDE9A antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

PDE9A antibody

Human Adrenal Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 4E1 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PDE9A antibody

Western blot using AP00660SU-N (1:2,000) against lysate from Insect cells transfected with the indicated human PDE isoform. Rabbit Serum Hu, Ms, Rt C, IP, WB
0.1 ml / €420.00
  Acris Antibodies GmbH

PDE9A Control Peptide

PDE9A
0.1 mg / €270.00
  Acris Antibodies GmbH

PDE9A antibody

Western blot using AP10254PU-N  (1:500). Rabbit Aff - Purified Hu, Ms, Rt IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

PDE9A antibody

Immunofluorescence of purified MaxPab antibody to PDE9A on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

PDE9A antibody

Immunofluorescence of purified MaxPab antibody to PDE9A on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PDE9A antibody

PDE9A Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PDE9A antibody

Western Blot analysis of PDE9A expression in transfected 293T cell line (H00005152-T02) by PDE9A MaxPab polyclonal antibody.

Lane 1: PDE9A transfected lysate(61.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PDE9A antibody

Immunoperoxidase of monoclonal antibody to PDE9A on formalin-fixed paraffin-embedded human cerebellum. [antibody concentration 3 ug/ml] Mouse IgG2a 1E1 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PDE9A antibody

PDE9A Rabbit Hu, Ms, Rt C, IP, WB
50 µl / €560.00
  Abnova Taiwan Corp.

PDE9A antibody

PDE9A Antibody Rabbit Serum Hu, Ms, Rt IP, P, WB
50 µl / €400.00
  Immuquest

PDE9A antibody

PDE9A Rabbit Aff - Purified Hu P
50 µg / €440.00
  Novus Biologicals Inc.

PDE9A antibody

PDE9A
50 µl / €140.00
  Novus Biologicals Inc.

PDE9A antibody

PDE9A Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, P, WB
25 µl / €220.00
  Novus Biologicals Inc.

PDE9A antibody

Western Blot: PDE9A Antibody [NBP1-52941] - This Anti-PDE9A antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PDE9A (transcript variant 13)

PDE9A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Items 1 to 20 of 46 total

per page
Page:
  1. 1
  2. 2
  3. 3
  • LinkedIn