PDF antibody
Principal name
PDF antibody
Alternative names for PDF antibody
PDF1A, Polypeptide deformylase, Peptide deformylase mitochondrial
SwissProt ID
Q9HBH1 (Human)
Gene ID
64146 (PDF)
Ncbi ID
Available reactivities
Available hosts
Available applications
ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of PDF antibody
Protein synthesis proceeds after formylation of methionine by methionyl-tR formyl transferase (FMT) and transfer of the charged initiator f-met tR to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of scent peptides. In eubacteria, deformylation of scent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a tural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. [provided by RefSeq].










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- Highly Validated (2)
Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA502988 | PDF antibody |
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PDF mouse monoclonal antibody, clone OTI3F3 (formerly 3F3) | |||||||
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Mouse | IgG2b | OTI3F3 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€379.00
|
OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA502989 | PDF antibody |
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PDF mouse monoclonal antibody, clone OTI3C12 (formerly 3C12) | |||||||
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Mouse | IgG1 | OTI3C12 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€350.00
|
OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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AP55140SU-N | PDF antibody |
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Rabbit | Serum | Hu | C, E, WB |
0.2 ml /
€400.00
|
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Acris Antibodies GmbH |
CRISPR
Catalog No. | Species | Donor Vector | |
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KN205788 | PDF - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN205788BN | PDF - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN205788LP | PDF - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN205788RB | PDF - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |