PDF antibody

Principal name

PDF antibody

Alternative names for PDF antibody

PDF1A, Polypeptide deformylase, Peptide deformylase mitochondrial

SwissProt ID

Q9HBH1 (Human)

Gene ID

64146 (PDF)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PDF antibody

Protein synthesis proceeds after formylation of methionine by methionyl-tR formyl transferase (FMT) and transfer of the charged initiator f-met tR to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of scent peptides. In eubacteria, deformylation of scent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a tural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. [provided by RefSeq].

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PDF antibody

Anti-PDF mouse monoclonal antibody (TA502988) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDF(RC205788 ). Mouse IgG2b OTI3F3 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PDF antibody

Anti-PDF mouse monoclonal antibody (TA502989) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDF(RC205788 ). Mouse IgG1 OTI3C12 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PDF antibody

PDF Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

PDF antibody

PDF MaxPab polyclonal antibody. Western Blot analysis of PDF expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PDF 293T Cell Transient Overexpression Lysate(Denatured)

PDF 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

5 Item(s)

per page
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