PDGFB antibody

Principal name

PDGFB antibody

Alternative names for PDGFB antibody

Platelet-derived growth factor subunit B, PDGF beta, PDGF B, PDGF-B, Platelet-derived growth factor beta, PDGF subunit B, Platelet-derived growth factor B chain, PDGF2, PDGF-2, c-Sis, SIS, Becaplermin

SwissProt ID

P01127 (Human), P12919 (Felca), P20034 (Pig), P31240 (Mouse), Q05028 (Rat), Q6Q7I7 (Canfa), Q95229 (Sheep)

Gene ID

5155 (PDGFB), 18591 (Pdgfb), 24628

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Fe (Feline), Mky (Monkey), Op (Opossum), Prim (Primate), Sh (Sheep), Bear, Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse, Sheep

Available applications

Paraffin Sections (P), Functional assay (FN), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), ELISA (detection) (E(detection))

Background of PDGFB antibody

PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene.

General readings

Van Steensel L., et al. (2012) J Clin Endocrinol Metab. 97(6): 37062-37071.Malabanan KP, et al. (2012) Am J Pathol. 180(6): 2590-7.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PDGFB (222-233) antibody

Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Fe, Hu, Mky, Ms, Op, Prim, Rt, Sh P
50 µg / €470.00
  Acris Antibodies GmbH

PDGFB (101-116) antibody

Figure 1. Formalin-fixed, paraffin-embedded human angiosarcoma stained with PDGF antibody (Cat. DP145) using peroxidase-conjugate and AEC. Note cytoplasmic staining of tumor cells. Rabbit Purified Hu, Rt C, P
1 ml / €590.00
  Acris Antibodies GmbH

PDGFB (101-116) antibody

Figure 1. Formalin-fixed, paraffin-embedded human angiosarcoma stained with PDGF antibody (Cat. DP145) using peroxidase-conjugate and AEC. Note cytoplasmic staining of tumor cells. Rabbit Purified Hu, Rt C, P
0.5 ml / €390.00
  Acris Antibodies GmbH

PDGFB antibody

  Rabbit polyclonal anti-PDGFB antibody  
Western blot analysis of extracts from NIH/3T3 cells, using PDGFB antibody (#TA314326).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Rabbit polyclonal anti-PDGF-BB antibody  
Western blot analysis using recombinant human PDGF-BB. Rabbit Purified Hu WB
0.2 mg / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Rabbit polyclonal anti-PDGF-BB antibody  
Western blot analysis using recombinant murine PDGF-BB. Lane 1: 50 ng, Lane 2: 250 ng, Lane 3: 1 ug. Rabbit Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Rabbit Polyclonal PDGF-B Antibody  
Western blot analysis of PDGF-B in rat liver tissue lysate with PDGF-B antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Anti-PDGFB Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human liver and ovarian cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using PDGFB antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Rabbit Polyclonal PDGFB Antibody  
Western blot analysis on NIH-3T3 cell lysate using PDGFB Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Rabbit anti-PDGFB Polyclonal Antibody  
Western blot analysis of extracts of A431 cell lines using PDGFB antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Biotinylated Anti-Human PDGF-BB Rabbit Polyclonal Antibody  
To detect hPDGF-BB by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1.0 ug/ml of this antibody is required.  This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant hPDGF-BB. Rabbit IgG Purified Hu E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Anti-Human PDGF-BB Rabbit Polyclonal Antibody  
To detect hPDGF-BB by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human PDGF-BB (TA328416) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hPDGF-BB. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Rabbit Polyclonal Anti-PDGFB Antibody - N-terminal region  
WB Suggested Anti-PDGFB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: 293T cell lysateThere is BioGPS gene expression data showing that PDGFB is expressed in HEK293T Rabbit IgG Purified Bov, Can, Hu, Ms, Rb, Rt, Sh P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PDGFB antibody

  Rabbit Polyclonal PDGFB Antibody  
ELISA: PDGFB Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

PDGFB (PDGF-BB / - AB) antibody

Staining of normal formalin fixed, paraffin embedded human skin with Rabbit anti Human PDGF BB Cat.-No AP05490PU-N) Rabbit IgG Purified Hu E, FN, P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

PDGFB antibody

 Immunohistochemistry (IHC) analysis of PDGFB antibody (Cat.-No.: AP06282PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PDGFB (PDGF-BB) antibody

PDGFB Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

PDGFB (PDGF-BB) antibody

PDGFB Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

PDGFB (PDGF-BB) antibody

Formalin-Fixed, Paraffin-Embedded Sections of normal Human skin stained with PDGF-BB antibody Cat.-No PP1062P Rabbit Aff - Purified Hu E, FN, P, WB
50 µg / €230.00
  Acris Antibodies GmbH

PDGFB (PDGF-BB) antibody

Formalin-Fixed, Paraffin-Embedded Sections of normal Human skin stained with PDGF-BB antibody Cat.-No PP1062P Rabbit Aff - Purified Hu E, FN, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

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