PDZD1 antibody

Principal name

PDZD1 antibody

Alternative names for PDZD1 antibody

PDZK1, NHERF3, NHERF-3, NHE-RF3, NaPi-Cap1, CAP70, PDZ domain-containing protein 1, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Sodium-hydrogen exchanger regulatory factor 3

SwissProt ID

Q3T0X8 (Bovin), Q5T2W1 (Human), Q865P3 (Rabit), Q9JIL4 (Mouse), Q9JJ40 (Rat)

Gene ID

5174 (PDZK1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of PDZD1 antibody

Scaffold or adaptor proteins recruits and/or anchor their binding partners to specific subcellular locations, serving as a platform to regulate interactions between proteins involved in diverse sigl transduction pathways, and PDZK1 (PDZ domain-containing protein 1) is a scaffold protein belonging to NHERFs family. PDZK1 expression is largely limited to epithelial cells and is mainly expressed in rel proximal epithelial cells, hepatocytes, and at a lower level in other epithelial as well as certain endothelial cells. PDZK1 has four PDZ domains which facilitates its interaction with its binding partners, including ion transporters (e.g. CFTR, OCTN1/OCTN2 etc) and several GPCRs (e.g. HTR2B, SSTR family members). Through its interaction with HDL and SR-BI, PDZK1 can play role in reverse cholesterol transport and for HDL-mediated vascular re-endothelialisation. When complex with SLC9A3R1, PDZK1 cluster proteins that are functiolly dependent in a mutual fashion and modulate the trafficking as well as the activity of associated membrane proteins. PDZK1 plays a role in cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 also implicates in connecting SCARB1 with cellular machineries for intracellular cholesterol transport and/or metabolism and regulation of proximal tubular +-dependent inorganic phosphate cotransport.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
LaLonde, D.P., et al. Mol. Biol. Cell 21(9):1519-1529(2010)
Polasek, O., et al. Croat. Med. J. 51(1):32-39(2010)
Gunjaca, G., et al. Croat. Med. J. 51(1):23-31(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PDZD1 antibody

Western blot analysis of extracts of various cell lines, using PDZK1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PDZD1 antibody

Western Blot: PDZK1 Antibody [TA336647] - WB analysis of PDZK1 in fetal  human liver lysate. Rabbit Purified Bov, Hu, Ms C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PDZD1 (1-520) antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1C3-2B11 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PDZD1 antibody

The cell lysates of HeLa (40ug) and 293T (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDZK1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b AT1A2 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

PDZD1 antibody

The cell lysates of HeLa (40ug) and 293T (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDZK1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b AT1A2 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

PDZD1 (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with PDZK1 Antibody (Center) Cat.-No AP53250PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PDZD1 antibody

PDZD1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PDZD1 antibody

Immunoperoxidase of monoclonal antibody to PDZK1 on formalin-fixed paraffin-embedded human transitional cell carcinoma tissue. [antibody concentration 5ug/ml] Mouse IgG1 1C3-2B11 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PDZD1 antibody

PDZK1 monoclonal antibody (M01), clone 1C3-2B11. Western Blot analysis of PDZK1 expression in human kidney. Mouse IgG1 1C3-2B11 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

PDZD1 antibody

Human 293T; WB Suggested Anti-PDZK1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: 293T cell lysate; PDZK1 antibody - N-terminal region (ARP41505_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PDZD1 (N-term) antibody

PDZD1 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PDZD1 antibody

PDZD1 Rabbit Serum Bov, Hu, Ms ICC/IF, P, WB
25 µl / €160.00
  Novus Biologicals Inc.

PDZD1 antibody

Immunohistochemistry: PDZK1 Antibody (EPR3751) [NBP1-40709] - Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- PDZK1 Rabbit IgG EPR3751 Hu F, ICC/IF, IP, P, WB
0.1 ml / €480.00
  Novus Biologicals Inc.

PDZD1 antibody

Western Blot: PDZK1 Antibody [NBP1-55286] - This Anti-PDZK1 antibody was used in Western Blot of 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PDZD1

PDZD1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PDZD1 (1-519, His-tag)

PDZD1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PDZD1 (1-519, His-tag)

PDZD1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

PDZD1

PDZD1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PDZD1

PDZD1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PDZK1 overexpression lysate

PDZK1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

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