PEA15 antibody

Principal name

PEA15 antibody

Alternative names for PEA15 antibody

Astrocytic phosphoprotein PEA-15, PED, Phosphoprotein enriched in diabetes

SwissProt ID

Q15121 (Human), Q5U318 (Rat), Q62048 (Mouse)

Gene ID

8682 (PEA15), 364052 (Pea15a), 18611

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of PEA15 antibody

PEA-15 (phosphoprotein enriched in astrocytes) exists in an non-phosphorylated form (N), and two phosphorylated forms, Pa and Pb. PEA-15 is an endogenous substrate for PKC, which mediates the transition from Pa to Pb. The level of PEA-15 phosphorylation changes upon depolymerization or stabilization of tubulins, indicating that PEA-15 co-localizes with microtubules. The first 80 amino acids of PEA-15 correspond to the death effector domain (DED), which is a domain found in proteins that regulate apoptotic signaling pathways. The DED domain is necessary for PEA-15 to block Ras suppression. Although PEA-15 is predominantly expressed in the central nervous system, low levels of PEA-15 are expressed in liver and kidney, and higher levels in muscle. PEA-15 is also referred to as PED, phosphoprotein enriched in diabetes, for its elevated expression in type 2 diabetic patients.

General readings

Beguinot F., et al. (2009) Am J Physiol Endocrinol Metab. 297(3):E592-601.
Ueno NT., et al. (2008) Cancer Res. 68(22):9302-10.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PEA15 antibody

  Rabbit polyclonal anti-PEA-15 antibody  
Immunohistochemistry analysis of paraffin-embedded human heart tissue using PEA-15 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PEA15 antibody

  Rabbit polyclonal PEA-15 (Ser104) antibody(Phospho-specific)  
Western blot analysis of extracts from COS cells, treated with TNF (20ng/ml, 5mins), using PEA-15 (Phospho-Ser104) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PEA15 antibody

  Rabbit Polyclonal Anti-PEA15 Antibody  
WB Suggested Anti-PEA15 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PEA15 antibody

Immunohistochemistry (IHC) analyzes of PEA-15 antibody (Cat.-No.: AP06559PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PEA15 (C-term) antibody

(LEFT) Western blot analysis of PEA-15 Antibody (C-term) (AP18148PU-N) in T47D cell line lysates (35ug/lane).PEA-15 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of PEA-15 Antibody (C-term) (AP18148PU-N) in mouse lung tissue lysates (35ug/lane).PEA-15 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PEA15 pSer104 antibody

Immunohistochemical analysis of paraffin-embedded human heart tissue using PEA-15 (Phospho-Ser104) antibody AP55709PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

PEA15 pSer104 antibody

Immunohistochemical analysis of paraffin-embedded human heart tissue using PEA-15 (Phospho-Ser104) antibody AP55709PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €270.00
  Acris Antibodies GmbH

PEA15 pSer116 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using PEA-15 (Phospho-Ser116) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

PEA15 pSer116 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using PEA-15 (Phospho-Ser116) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

PEA15 pSer104 antibody

Immunohistochemistry analysis of paraffin-embedded human heart, using PEA-15 (Phospho-Ser104) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

PEA15 pSer104 antibody

Immunohistochemistry analysis of paraffin-embedded human heart, using PEA-15 (Phospho-Ser104) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

PEA15 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PEA-15 (Ab-116) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

PEA15 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PEA-15 (Ab-116) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

PEA15 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using PEA-15 (Ab-104) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €230.00
  Assay Biotech

PEA15 antibody

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using PEA-15 (Ab-104) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €330.00
  Assay Biotech

PEA15 antibody

Immunofluorescence analysis of MCF7 cells, using PEA15 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €230.00
  Assay Biotech

PEA15 antibody

Immunofluorescence analysis of MCF7 cells, using PEA15 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Pea15a - mouse gene knockout kit via CRISPR

Pea15a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pea15a - mouse gene knockout kit via CRISPR

Pea15a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pea15a - mouse gene knockout kit via CRISPR

Pea15a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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