PEAR1 antibody

Principal name

PEAR1 antibody

Alternative names for PEAR1 antibody

MEGF12, Platelet endothelial aggregation receptor 1, Multiple epidermal growth factor-like domains protein 12, Multiple EGF-like domains protein 12

SwissProt ID

Q5VY43 (Human), Q8VIK5 (Mouse)

Gene ID

375033 (PEAR1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PEAR1 antibody

PEAR1 Antibody: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that sigls upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

General readings

Johnson, A.D., et al. Nat. Genet. 42(7):608-613(2010)
Jones, C.I., et al. Blood 114(7):1405-1416(2009)
Herrera-Galeano, J.E., et al. Arterioscler. Thromb. Vasc. Biol. 28(8):1484-1490(2008)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PEAR1 (C-term) antibody

PEAR1 Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PEAR1 control peptide

50 µg / €160.00
  Acris Antibodies GmbH

PEAR1 (C-term) antibody

PEAR1 Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PEAR1 antibody

PEAR1 Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

4 Item(s)

per page
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