Peptidase 1 / DERP1 antibody

Principal name

Peptidase 1 / DERP1 antibody

Alternative names for Peptidase 1 / DERP1 antibody

Allergen Der p I, Major mite fecal allergen Der p 1

SwissProt ID

P08176 (Derpt)

Ncbi ID

6956

Available hosts

Human

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Peptidase 1 / DERP1 antibody

House-dust mite allergy belongs to the most common allergies worldwide which affect more than 50% of all allergic patients. House dust mite allergens play an important role in inducing IgE-mediated sensitization and the development of bronchial hyper responsiveness and asthma, perennial rhinitis, and atopic dermatitis. Allergic patients’ sera (IgE) recognize the house-dust mite Dermatophagoïdes Pteronyssinus Derp1 and Derp2. The key event in these reactions is the cross-linking of IgE antibodies on effector cells by allergens, which induces a release of biologically active mediators like histamine and leukotrienes leading to different symptoms of allergy. In vivo studies have shown that the cysteine peptidase activity of group 1 house-dust mite allergens contributes to their allergenicity.
(Chapman MD, 1980; J. Immunol., 125: 587-592; Hales BJ, Thomas WR., 1997; Clin. Exp. Allergy, 27(8):868- 875; Doull IJ. et al, 1997; Allergy, 52,220; Custovic A, 1996; J. Allergy Clin. Immunol., 98: 64-72; Szalai K. et al., 2008; Mol. Immunol. 45:5, 1308-17).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Peptidase 1 / DERP1 antibody

Human monoclonal antibodies were tested in an indirect ELISA to detect Dermatophagoïdes Pteronyssinus antigens : crude extract (DPT) or recombinantDerp1or Derp2 Human IgG1 H.AK6.A3.F4 Purified E, WB
50 µg / €440.00
  Dendritics SAS

Peptidase 1 / DERP1 antibody

Human monoclonal antibodies were tested in an indirect ELISA to detect Dermatophagoïdes Pteronyssinus antigens : crude extract (DPT) or recombinantDerp1or Derp2 Human IgG1 H.AK6.A3.F4 Purified E, WB
0.1 mg / €590.00
  Dendritics SAS

Peptidase 1 / DERP1 antibody

Human monoclonal antibodies were tested in an indirect ELISA to detect Dermatophagoïdes Pteronyssinus antigens : crude extract (DPT) or recombinantDerp1or Derp2 Human IgG1 H.AA.IV7A3 Purified E, WB
50 µg / €440.00
  Dendritics SAS

Peptidase 1 / DERP1 antibody

Human monoclonal antibodies were tested in an indirect ELISA to detect Dermatophagoïdes Pteronyssinus antigens : crude extract (DPT) or recombinantDerp1or Derp2 Human IgG1 H.AA.IV7A3 Purified E, WB
0.1 mg / €590.00
  Dendritics SAS

Peptidase 1 / DERP1 antibody

Human monoclonal antibodies were tested in an indirect ELISA to detect Dermatophagoïdes Pteronyssinus antigens : crude extract (DPT) or recombinantDerp1or Derp2 Human IgG1 H.AK5.C Purified E, WB
50 µg / €440.00
  Dendritics SAS

Peptidase 1 / DERP1 antibody

Human monoclonal antibodies were tested in an indirect ELISA to detect Dermatophagoïdes Pteronyssinus antigens : crude extract (DPT) or recombinantDerp1or Derp2 Human IgG1 H.AK5.C Purified E, WB
0.1 mg / €590.00
  Dendritics SAS

6 Item(s)

per page
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