Periplakin / PPL antibody

Principal name

Periplakin / PPL antibody

Alternative names for Periplakin / PPL antibody

KIAA0568, 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein

SwissProt ID

O60437 (Human), Q9R269 (Mouse)

Gene ID

5493 (PPL), 15493 (Hsd3b2)

Available reactivities

Hu (Human), Bov (Bovine)

Available hosts

Rabbit, Guinea Pig

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Periplakin / PPL antibody

Peroplakin is a component of the cornified envelope of keratinocytes. It may link the cornified envelope to desmosomes and intermediate filaments and may act as a localization signal in PKB/AKT-mediated signaling. [from:] Endogenous periplakin localizes to different cellular compartments, including plasma membrane, intermediate filament structures, the nucleus and mitochondria. Overexpression of the C-terminal part of periplakin, encompassing the PKB binding region, results in predominant intermediate filament localization and little nuclear staining. Periplakin is expressed in epithelial cells, together with envoplakin, the precursor of the epidermal cornified envelope. Furthermore, periplakin has been shown to be a target antigen in paraneoplastic pemphigus, and in keratinocytes it localizes at desmosomes and the interdesmosomal plasma membrane. [from:]

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Periplakin / PPL antibody

Periplakin / PPL Guinea Pig Serum Bov, Hu C, ICC/IF, IP, WB
0.1 ml / €370.00
  Acris Antibodies GmbH

Periplakin / PPL antibody

Periplakin / PPL Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Periplakin / PPL antibody

Periplakin / PPL Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.


Catalog No.    

PPL overexpression lysate

PPL overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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