Periplakin / PPL antibody

Principal name

Periplakin / PPL antibody

Alternative names for Periplakin / PPL antibody

KIAA0568, 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein

SwissProt ID

O60437 (Human), Q9R269 (Mouse)

Gene ID

5493 (PPL), 19041 (Ppl)

Available reactivities

Bov (Bovine), Hu (Human), Por (Porcine)

Available hosts

Guinea Pig, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB)

Background of Periplakin / PPL antibody

PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Periplakin / PPL antibody

  Rabbit Polyclonal Anti-PPL Antibody  
WB Suggested Anti-PPL Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: MCF7 cell lysate.PPL is supported by BioGPS gene expression data to be expressed in MCF7 Rabbit IgG Purified Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

Periplakin / PPL antibody

Periplakin / PPL Guinea Pig Serum Bov, Hu C, ICC/IF, IP, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

Periplakin / PPL antibody

Human MCF-7; WB Suggested Anti-PPL Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: MCF7 cell lysate. PPL is supported by BioGPS gene expression data to be expressed in MCF7.; PPL antibody - middle region (ARP42061_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Lysates

Catalog No.    

PPL overexpression lysate

PPL overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

4 Item(s)

per page
  • LinkedIn