Peroxiredoxin-2 / PRDX2 antibody

Principal name

Peroxiredoxin-2 / PRDX2 antibody

Alternative names for Peroxiredoxin-2 / PRDX2 antibody

PRDX-2, Prx2, Prx-2, TSA, PRP, NKEF-B, NKEFB, TDPX1, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, Natural killer cell-enhancing factor B

SwissProt ID

P32119 (Human), P35704 (Rat), P52552 (Pig), Q61171 (Mouse), Q9BGI3 (Bovin)

Gene ID

7001 (PRDX2), 21672 (Prdx2), 29338

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Hst (Hamster), Bov (Bovine), Por (Porcine), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit), Sh (Sheep), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Peroxiredoxin-2 / PRDX2 antibody

PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a protein that in humans is encoded by the PRDX2 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The Prdx2 -/- mice were healthy in appearance and fertile. Choi et al. (2005) demonstrated that PRDX2 is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug. 

General readings

Kim K., et al. (2009), Oncol Rep, 21(6):1391-6.
Kim JH., et al. (2008). Clin Cancer Res. 14(8):2326-33.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Peroxiredoxin-2 / PRDX2 (C-term) antibody

  Rabbit polyclonal PRDX2 Antibody (C-term)  
Formalin-fixed and paraffin-embedded human brain tissue reacted with PRDX2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

  Rabbit Polyclonal Peroxiredoxin 2 Antibody  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PRDX2 rabbit polyclonal antibody. (TA590354) Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 (C-term) antibody

  Goat Polyclonal Antibody against PRDX2  
TA303117 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

  PRDX2 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using PRDX2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

  Rabbit Polyclonal Anti-PRDX2 Antibody  
WB Suggested Anti-PRDX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate.PRDX2 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Sh, Ye, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

  Rabbit Polyclonal Anti-PRDX2 Antibody  
Peroxiredoxin-2 / PRDX2 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prdx2 - mouse gene knockout kit via CRISPR

Prdx2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Prdx2 - mouse gene knockout kit via CRISPR

Prdx2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prdx2 - mouse gene knockout kit via CRISPR

Prdx2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prdx2 - mouse gene knockout kit via CRISPR

Prdx2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Peroxiredoxin-2 / PRDX2 (transcript variant 1)

  Recombinant protein of human peroxiredoxin 2 (PRDX2), nuclear gene encoding mitochondrial protein, transcript variant 1  
Peroxiredoxin-2 / PRDX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 (1-198)

Peroxiredoxin-2 / PRDX2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €990.00
  Acris Antibodies GmbH

Peroxiredoxin-2 / PRDX2 (1-198)

Peroxiredoxin-2 / PRDX2 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PRDX2 (mGFP-tagged) - Human peroxiredoxin 2 (PRDX2), nuclear gene encoding mitochondrial protein, transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, PRDX2 (mGFP-tagged) - Human peroxiredoxin 2 (PRDX2), nuclear gene encoding mitochondrial protein, transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, PRDX2 (Myc-DDK tagged) - Human peroxiredoxin 2 (PRDX2), nuclear gene encoding mitochondrial protein, transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PRDX2 (Myc-DDK tagged) - Human peroxiredoxin 2 (PRDX2), nuclear gene encoding mitochondrial protein, transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Prdx2 (GFP-tagged) - Mouse peroxiredoxin 2 (Prdx2), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, Prdx2 (GFP-tagged) - Mouse peroxiredoxin 2 (Prdx2), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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