Peroxiredoxin-2 / PRDX2 antibody

Principal name

Peroxiredoxin-2 / PRDX2 antibody

Alternative names for Peroxiredoxin-2 / PRDX2 antibody

PRDX-2, Prx2, Prx-2, TSA, PRP, NKEF-B, NKEFB, TDPX1, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, Natural killer cell-enhancing factor B

SwissProt ID

P32119 (Human), P35704 (Rat), P52552 (Pig), Q61171 (Mouse), Q9BGI3 (Bovin)

Gene ID

7001 (PRDX2), 21672 (Prdx2), 29338

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Hst (Hamster), Bov (Bovine), Por (Porcine), African clawed frog

Available hosts

Rabbit, Mouse, Goat, Chicken

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Functional assay (FN), Frozen Sections (C)

Background of Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.

General readings

Kato S, Kato M, Abe Y, Matsumura T, Nishino T, Aoki M, Itoyama Y, Asayama K, Awaya A, Hirano A, Ohama E. , Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models. ,Acta Neuropathol (Berl). 2005 Jun 28; [Epub ahead of print] , PMID: 15983830

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Peroxiredoxin-2 / PRDX2 (C-term) antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with PRDX2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PRDX2 rabbit polyclonal antibody. (TA590354) Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Immunoperoxidase of monoclonal antibody to PRDX2 on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 1ug/ml] Mouse IgG1 4E10-2D2 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 (C-term) antibody

TA303117 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
20 µg / €200.00
  Acris Antibodies GmbH

Peroxiredoxin-2 / PRDX2 (C-term) antibody

TA303117 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Western blot analysis of extracts of various cell lines, using PRDX2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Western Blot analysis of PRDX2 expression in transfected 293T cell line (H00007001-T02) by PRDX2 MaxPab polyclonal antibody.

Lane 1: PRDX2 transfected lysate(21.90 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Detection limit for recombinant GST tagged PRDX2 is approximately 3ng/ml as a capture antibody. Mouse IgG1 S2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Immunoblot analysis of cell lysates. Lane 1 : Hela cell lysate, lane 1 : Hela cell lysate, lane 2 : NIH/3T3 cell lysate, lane 3 : C6 cell lysate and lane 4 : A-431 cell lysate. Rabbit Hu, Ms, Rt WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

PRDX2 polyclonal antibody ( Cat # PAB7050 ) ( 1 µg/ml ) staining of human brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Rabbit Hst, Hu, Ms, Rt C, WB
0.1 ml / €740.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Human Liver; Liver; PRDX2 antibody - middle region (ARP48281_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Rabbit Hu E, WB
50 µg / €400.00
  Novus Biologicals Inc.

Peroxiredoxin-2 / PRDX2 antibody

Western Blot: PRDX2 Antibody [NB100-40806] - NB100-40806 (1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Peroxiredoxin-2 / PRDX2 antibody

Figure 1 shows staining of Prx 2 in TSU-Pr1 cells using NB100-74494. Rabbit Serum Hu ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Peroxiredoxin-2 / PRDX2 antibody

Western Blot: peroxiredoxin 2 Antibody [NBP1-54337] - This Anti-PRDX2 antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Peroxiredoxin-2 / PRDX2 (transcript variant 1)

Peroxiredoxin-2 / PRDX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 (1-198)

Peroxiredoxin-2 / PRDX2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €990.00
  Acris Antibodies GmbH

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