Peroxiredoxin-2 / PRDX2 antibody

Principal name

Peroxiredoxin-2 / PRDX2 antibody

Alternative names for Peroxiredoxin-2 / PRDX2 antibody

PRDX-2, Prx2, Prx-2, TSA, PRP, NKEF-B, NKEFB, TDPX1, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, Natural killer cell-enhancing factor B

SwissProt ID

P32119 (Human), P35704 (Rat), P52552 (Pig), Q61171 (Mouse), Q9BGI3 (Bovin)

Gene ID

7001 (PRDX2), 21672 (Prdx2), 29338

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Hst (Hamster), Bov (Bovine), Por (Porcine), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit), Sh (Sheep), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Peroxiredoxin-2 / PRDX2 antibody

PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a protein that in humans is encoded by the PRDX2 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The Prdx2 -/- mice were healthy in appearance and fertile. Choi et al. (2005) demonstrated that PRDX2 is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug. 

General readings

Kim K., et al. (2009), Oncol Rep, 21(6):1391-6.
Kim JH., et al. (2008). Clin Cancer Res. 14(8):2326-33.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Peroxiredoxin-2 / PRDX2 (C-term) antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with PRDX2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PRDX2 rabbit polyclonal antibody. (TA590354) Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Immunoperoxidase of monoclonal antibody to PRDX2 on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 1ug/ml] Mouse IgG1 4E10-2D2 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 (C-term) antibody

TA303117 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Western blot analysis of extracts of various cell lines, using PRDX2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

WB Suggested Anti-PRDX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate.PRDX2 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Sh, Ye, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Western Blot analysis of PRDX2 expression in transfected 293T cell line (H00007001-T02) by PRDX2 MaxPab polyclonal antibody.

Lane 1: PRDX2 transfected lysate(21.90 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Detection limit for recombinant GST tagged PRDX2 is approximately 3ng/ml as a capture antibody. Mouse IgG1 S2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Immunoblot analysis of cell lysates. Lane 1 : Hela cell lysate, lane 1 : Hela cell lysate, lane 2 : NIH/3T3 cell lysate, lane 3 : C6 cell lysate and lane 4 : A-431 cell lysate. Rabbit Hu, Ms, Rt WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

PRDX2 polyclonal antibody ( Cat # PAB7050 ) ( 1 µg/ml ) staining of human brain lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Rabbit Hst, Hu, Ms, Rt C, WB
0.1 ml / €740.00
  Abnova Taiwan Corp.

Peroxiredoxin-2 / PRDX2 antibody

Human Liver; Liver; PRDX2 antibody - middle region (ARP48281_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Peroxiredoxin-2 / PRDX2 antibody

Peroxiredoxin-2 / PRDX2 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

CRISPR

Catalog No. Species Donor Vector  

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRDX2 - human gene knockout kit via CRISPR

PRDX2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Peroxiredoxin-2 / PRDX2 (transcript variant 1)

Peroxiredoxin-2 / PRDX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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