Peroxiredoxin-4 / PRDX4 antibody

Principal name

Peroxiredoxin-4 / PRDX4 antibody

Alternative names for Peroxiredoxin-4 / PRDX4 antibody

PRDX-4, Prx4, Prx-4, Prx-IV, AOE37-2, Thioredoxin peroxidase AO372,Thioredoxin-dependent peroxide reductase A0372, Antioxidant enzyme AOE372

SwissProt ID

O08807 (Mouse), Q13162 (Human), Q9BGI2 (Bovin)

Gene ID

10549 (PRDX4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Ze (Zebrafish), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Flow Cytometry (F), Immunoprecipitation (IP), Frozen Sections (C), ELISA (detection) (E(detection))

Background of Peroxiredoxin-4 / PRDX4 antibody

PRDX4(peroxiredoxin 4) also known as AOE37-2. The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. Functional analysis showed that PRDX4 protects glutamine synthetase from inactivation. Yeast 2-hybrid, immunoprecipitation, and immunoblot analyses indicated that PRDX4 and PRDX1 are capable of homodimerization and heterodimerization with each other but not with the mitochondrial PRDX3. Gel mobility shift and immunoblot analysis found that PRDX4 depletes NFKB binding activity together with a reduction in the amounts of p50, p65, and phosphorylated IKBA, as well as a reduction in the expression of HIV-1 viral proteins. Expression of PRDX4, alone or with PRDX1, increased the resistance of yeast cells to oxidant-induced toxicity. Jin et al. (1997)suggested PRDX4 modulates IKBA phosphorylation in the cytoplasm and thus affects a peroxiredoxin-dependent redox step.

General readings

Wang HQ., et al. (2009) FEBS Lett. 583(9):1511-5.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Peroxiredoxin-4 / PRDX4 antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-PRDX4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500684) Mouse IgG1 OTI9A3 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Peroxiredoxin-4 / PRDX4 (Center) antibody

PRDX4 Antibody (Center) (Cat. #AP53439PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRDX4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Peroxiredoxin-4 / PRDX4 antibody

Predicted band size: 31 kDa . Positive control: HepG2 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-4 / PRDX4 antibody

Western blot analysis of extracts of variouscell lines, using PRDX4 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-4 / PRDX4 antibody

Host: Rabbit; Target Name: PRDX4; Sample Tissue: COLO205 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml PRDX4 is supported by BioGPS gene expression data to be expressed in COLO205 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-4 / PRDX4 antibody

WB Suggested Anti-PRDX4 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Peroxiredoxin-4 / PRDX4 antibody

Immunofluorescence of purified MaxPab antibody to PRDX4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Immunoprecipitation of PRDX4 transfected lysate using anti-PRDX4 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PRDX4 MaxPab mouse polyclonal antibody (B01) (H00010549-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Immunoperoxidase of monoclonal antibody to PRDX4 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Mouse IgG3 2C12 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

PRDX4 monoclonal antibody (M01), clone 2C12. Western Blot analysis of PRDX4 expression in human liver. Mouse IgG3 2C12 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Peroxiredoxin-4 / PRDX4 Mouse IgG1 4C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Immunoprecipitation analysis of Hela cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with PRDX4 monoclonal antibody, clone 1A1 ( Cat # MAB0673 ). Mouse IgG3 1A1 Hu IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Immunocytochemical staining of HeLa cells using PRDX4 monoclonal antibody, clone 3A1 ( Cat # MAB0674 ). Mouse IgG1 3A1 Hu ICC/IF, IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Immunoblot analysis of cell lysates. Lane 1 : Hela cell lysate, lane 2 : 293T cell lysate and lane 3 : Jurkat cell lysate. Mouse IgG1 7A1 Hu E, IP, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Immunoblot analysis of cell lysates. Lane 1 : HeLa cell lysate. Lane 2 : Jurkat cell lysate. Lane 3 : Mouse brain. Rabbit Hu C, IP, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Peroxiredoxin-4 / PRDX4 antibody

Peroxiredoxin-4 / PRDX4 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

Peroxiredoxin-4 / PRDX4 antibody

ELISA: Peroxiredoxin-4 Antibody [28960002] Rabbit Hu E
50 µg / €440.00
  Novus Biologicals Inc.

Peroxiredoxin-4 / PRDX4 antibody

Peroxiredoxin-4 / PRDX4 Mouse 3A1 Hu IP, P
0.1 mg / €530.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Peroxiredoxin-4 / PRDX4

Peroxiredoxin-4 / PRDX4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Peroxiredoxin-4 / PRDX4

Peroxiredoxin-4 / PRDX4 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

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