PFKFB1 antibody

Principal name

PFKFB1 antibody

Alternative names for PFKFB1 antibody

F6PK, PFRX, PFK/FBPase 1, PFK-2 liver, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

SwissProt ID

P07953 (Rat), P16118 (Human), P49872 (Bovin), P70266 (Mouse)

Gene ID

5207 (PFKFB1), 18639 (Pfkfb1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Mky (Monkey), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of PFKFB1 antibody

PFKFB (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) is a bifunctional enzyme, having both kinase and phosphatase activities residing on the same enzyme subunit but having distinct active sites. PFKFB regulates the steady-state concentration of fructose-2,6-bisphosphate, a potent activator of a key regulatory enzyme of glycolysis, phosphofructokinase. To date, four PFKFB isozymes (PFKFB 1-4) have been described, which show differences in their tissue distribution and kinetic properties in response to allosteric effectors and hormonal signals. Among the PFKFB's PFKFB3 has the highest kinase:phosphatase ratio, in part because it lacks the characteristic serine phosphorylation site near the N-terminal that down-modulates kinase activity. PFKFB3 was first described in the rapidly growing placenta. The glucolitic rate in placenta is accelerated by anoxia and by maternal diabetes. Cancer cells maintain a high glycolytic rate even in the presence of oxygen, a phenomenon known as the Warburg effect. The glycolytic rate in the placenta, another fast-growing tissue, is accelerated by anoxia and by maternal diabetes.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PFKFB1 antibody

  Rabbit polyclonal anti-PFKFB1 antibody  
Western blot analysis of extracts from HUVEC cells and Jurkat cells, using PFKFB1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PFKFB1 antibody

  Rabbit polyclonal anti-PFKFB1/4 antibody  
Western blot analysis of extracts from HeLa cells, HepG2 cells, COLO205 cells and 293 cells, using PFKFB1/4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PFKFB1 antibody

  Rabbit Polyclonal Anti-PFKFB1/4 Antibody  
PFKFB1 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PFKFB1 antibody

  Rabbit Polyclonal Anti-PFKFB1 Antibody  
PFKFB1 Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PFKFB1 (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PFKFB1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PFKFB1 (Center) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PFKFB1 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PFKFB1 (Liver) antibody

Immunohistochemistry: AP20411PU-N PFK-2 liv antibody staining of Paraffin-Embedded Human liver carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PFKFB1 antibody

Western blot analysis of extracts from HeLa/HepG2/COLO205/293 cells, using PFKFB1/4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

PFKFB1/4 antibody

Western blot (WB) analysis of PFKFB1/4 antibody (Cat.-No.: AP06742PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PFKFB1/4 antibody

Western blot analysis of extracts from HeLa/HepG2/COLO205/293 cells, using PFKFB1/4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PFKFB1 - human gene knockout kit via CRISPR

PFKFB1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PFKFB1 - human gene knockout kit via CRISPR

PFKFB1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PFKFB1 - human gene knockout kit via CRISPR

PFKFB1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PFKFB1 - human gene knockout kit via CRISPR

PFKFB1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pfkfb1 - mouse gene knockout kit via CRISPR

Pfkfb1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pfkfb1 - mouse gene knockout kit via CRISPR

Pfkfb1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pfkfb1 - mouse gene knockout kit via CRISPR

Pfkfb1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pfkfb1 - mouse gene knockout kit via CRISPR

Pfkfb1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PFKFB1

  Recombinant protein of human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1)  
PFKFB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PFKFB1 (full length, N-term HIS tag)

  Purified recombinant protein of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
PFKFB1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

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