PGAP3 antibody

Principal name

PGAP3 antibody

Alternative names for PGAP3 antibody

CAB2, PERLD1, COS16 homolog, Post-GPI attachment to proteins factor 3, Gene coamplified with ERBB2 protein, PER1-like domain-containing protein 1

SwissProt ID

A2A559 (Mouse), A7YWP2 (Bovin), A8WFS8 (Danre), Q68EV0 (Xenla), Q7K0P4 (Drome), Q96FM1 (Human)

Gene ID

93210 (PGAP3)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Dot blot (Dot), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PGAP3 antibody

Certain loci on human chromosome 17q12 are frequently amplified in various types of cancers. One of such loci is PP1R1B-ERBB2-GRB7 which is greatly amplified in gastric and breast cancer. Search of other genes that reside close to this recombination hot spot or “fragile loci” led to discovery of several genes, one of these genes is a new theoretical protein MGC9753 is localized on chromosome 17 at cytogenetic location of 17q21.2. The detailed analyses of the amplicon structure in 330 breast tumors samples revealed a 280 kb common region of amplification that contains 10 genes that include 8 known genes. A highly significant association between amplification and expression levels was observed for 6 genes including ERBB2 and 2 uncharacterized hypothetical proteins, MGC9753 and MGC14832 in breast carcinoma and human gastric cancer samples (1, 2).
MGC9753 is located on human chromosome 17q12 and is in the amplicon cluster consist of PPP1R1B-STARD3-TCAP-PNMT-MGC9753-ERBB2-MGC14832-GRB7 with in the 120 kb region locus on human chromosome 17q12. The MGC9753 protein is a 7 transmembrane receptor with an extracellular six-cystein domain (3). The human and mouse MGC9753 protein is a 320 amino acid 7-transmembrane protein with 8 exxons exhibiting 90.6% total maino acid identity with human CAB2 aberrant protein, which lacked the 3rd transmembrane domain due to a frame shift mutation with in the ORF (3).

General readings

Benusiglio,P.R., (2006) Br. J. Cancer 95 (12), 1689-1695

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PGAP3 antibody

WB Suggested Anti-PGAP3 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PGAP3 antibody

WB Suggested Anti-PGAP3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PGAP3 control peptide

PGAP3
0.25 mg / €250.00
  Acris Antibodies GmbH

PGAP3 (N-term) antibody

PGAP3 Rabbit Aff - Purified Hu Dot, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

PGAP3 control peptide

PGAP3
0.25 mg / €250.00
  Acris Antibodies GmbH

PGAP3 antibody

PGAP3 Rabbit Aff - Purified Hu Dot, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

PGAP3 control peptide

PGAP3
0.25 mg / €250.00
  Acris Antibodies GmbH

PGAP3 (C-term) antibody

PGAP3 Rabbit Aff - Purified Hu Dot, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

PGAP3 antibody

Human HeLa; WB Suggested Anti-PERLD1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Hela cell lysate; PERLD1 antibody - N-terminal region (ARP50188_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

PGAP3 antibody

Human THP-1; WB Suggested Anti-PERLD1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: THP-1 cell lysate; PERLD1 antibody - N-terminal region (ARP50189_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PGAP3 antibody

ELISA: PGAP3 Antibody [21670002] Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

PGAP3 antibody

Western Blot: PGAP3 Antibody [NBP1-69334] - This Anti-PERLD1 antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

PGAP3 antibody

Western Blot: PGAP3 Antibody [NBP1-69622] - This Anti-PERLD1 antibody was used in Western Blot of THP-1     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

PGAP3 antibody

Immunohistochemistry-Paraffin: PGAP3 Antibody [NBP1-86692] Immunohistochemical staining of human duodenum shows cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PGAP3

PGAP3 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PGAP3 overexpression lysate

PGAP3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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