PGLYRP1 / PGRPS antibody

Principal name

PGLYRP1 / PGRPS antibody

Alternative names for PGLYRP1 / PGRPS antibody

Peptidoglycan recognition protein, PGRP-S, PGLYRP, PGRP, TNFSF3L

SwissProt ID

O75594 (Human), O88593 (Mouse), Q8SPP7 (Bovin), Q9JLN4 (Rat)

Gene ID

8993 (PGLYRP1), 21946 (Pglyrp1), 84387

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of PGLYRP1 / PGRPS antibody

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, thus, it is an excellent target for recognition by the eukaryotic inte immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-Ib) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood. PGRP-S is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. However, PGRP-S may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50-100 times higher than in neutrophils.

General readings

Lu X, Wang M, Qi J, Wang H, Li X, Gupta D, Dziarski R.
Peptidoglycan recognition proteins are a new class of human bactericidal proteins.
J Biol Chem. 2006 Mar 3;281(9):5895-907. Epub 2005 Dec 14.
PMID: 16354652

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PGLYRP1 / PGRPS (C-term) antibody

TA305756 (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS antibody

Western Blot: PGRP Antibody (188C424) [TA336460] - Analysis using PGRP-S antibody. Lysate from human Jurkat cells probed with PGRP-S antibody at 2 ug/ml. Mouse IgG3 188C424 Purified Hu, Ms C, F, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS antibody

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Hela cells, K562 cells, human fetal liver tissue, Primary antibody: (PGLYRP1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS antibody

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (PGLYRP1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS (C-term) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Purified Can, Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PGLYRP1 / PGRPS antibody

Western Blot analysis of PGLYRP1 expression in transfected 293T cell line (H00008993-T01) by PGLYRP1 MaxPab polyclonal antibody.

Lane 1: PGLYRP1 transfected lysate(21.56 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

PGLYRP1 / PGRPS Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

Western Blot analysis of PGLYRP1 expression in transfected 293T cell line (H00008993-T02) by PGLYRP1 MaxPab polyclonal antibody.

Lane 1: PGLYRP1 transfected lysate(21.56 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

PGLYRP1 / PGRPS Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

Western Blot analysis of PGLYRP1 expression in transfected 293T cell line (H00008993-T03) by PGLYRP1 MaxPab polyclonal antibody.

Lane 1: PGLYRP1 transfected lysate(21.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

Western blot analysis of PGLYRP1 in tissue lysates from mouse spleen using PGLYRP1 monoclonal antibody, clone 188C424 ( Cat # MAB0069 ) at a dilution of 2 µg/ml. Mouse IgG1 188C424 Hu, Ms F, ICC/IF, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

PGLYRP1 polyclonal antibody ( Cat # PAB11571 ) ( 0.3 µg/ml ) staining of Jurkat lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

PGLYRP1 - human gene knockout kit via CRISPR

  PGLYRP1 - human gene knockout kit via CRISPR  
PGLYRP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PGLYRP1 - human gene knockout kit via CRISPR

  PGLYRP1 - human gene knockout kit via CRISPR  
PGLYRP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PGLYRP1 - human gene knockout kit via CRISPR

  PGLYRP1 - human gene knockout kit via CRISPR  
PGLYRP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pglyrp1 - mouse gene knockout kit via CRISPR

Pglyrp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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