PGLYRP1 / PGRPS antibody

Principal name

PGLYRP1 / PGRPS antibody

Alternative names for PGLYRP1 / PGRPS antibody

Peptidoglycan recognition protein, PGRP-S, PGLYRP, PGRP, TNFSF3L

SwissProt ID

O75594 (Human), O88593 (Mouse), Q8SPP7 (Bovin), Q9JLN4 (Rat)

Gene ID

8993 (PGLYRP1), 899353 (acpS)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of PGLYRP1 / PGRPS antibody

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRPS, PGRPIA, and PGRP-I-beta) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood. PGRPS is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. However, PGRPS may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50–100 times higher than in neutrophils.

General readings

Lu X, Wang M, Qi J, Wang H, Li X, Gupta D, Dziarski R.
Peptidoglycan recognition proteins are a new class of human bactericidal proteins.
J Biol Chem. 2006 Mar 3;281(9):5895-907. Epub 2005 Dec 14.
PMID: 16354652

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PGLYRP1 / PGRPS (C-term) antibody

TA305756 (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS antibody

Western Blot: PGRP Antibody (188C424) [TA336460] - Analysis using PGRP-S antibody. Lysate from human Jurkat cells probed with PGRP-S antibody at 2 ug/ml. Mouse IgG3 188C424 Purified Hu, Ms C, F, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS (C-term) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Purified Can, Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PGLYRP1 / PGRPS antibody

Western Blot analysis of PGLYRP1 expression in transfected 293T cell line (H00008993-T01) by PGLYRP1 MaxPab polyclonal antibody.

Lane 1: PGLYRP1 transfected lysate(21.56 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

PGLYRP1 / PGRPS Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

Western Blot analysis of PGLYRP1 expression in transfected 293T cell line (H00008993-T02) by PGLYRP1 MaxPab polyclonal antibody.

Lane 1: PGLYRP1 transfected lysate(21.56 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

PGLYRP1 / PGRPS Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

Western Blot analysis of PGLYRP1 expression in transfected 293T cell line (H00008993-T03) by PGLYRP1 MaxPab polyclonal antibody.

Lane 1: PGLYRP1 transfected lysate(21.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

Western blot analysis of PGLYRP1 in tissue lysates from mouse spleen using PGLYRP1 monoclonal antibody, clone 188C424 ( Cat # MAB0069 ) at a dilution of 2 µg/ml. Mouse IgG1 188C424 Hu, Ms F, ICC/IF, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

PGLYRP1 polyclonal antibody ( Cat # PAB11571 ) ( 0.3 µg/ml ) staining of Jurkat lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS antibody

Immunohistochemistry-Paraffin: PGRP Antibody [NBP1-20962] - (3.8ug/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PGLYRP1 / PGRPS antibody

Immunohistochemistry-Paraffin: PGRP Antibody [NBP1-92261] Immunohistochemical staining of human bone marrow shows strong cytoplasmic and nuclear positivity in hematopoietic cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PGLYRP1 / PGRPS

PGLYRP1 / PGRPS Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PGLYRP1 293T Cell Transient Overexpression Lysate(Denatured)

PGLYRP1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

PGLYRP1 overexpression lysate

PGLYRP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PGLYRP 293T Cell Transient Overexpression Lysate(Denatured)

PGLYRP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

20 Item(s)

per page
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