PGLYRP1 / PGRPS antibody

Principal name

PGLYRP1 / PGRPS antibody

Alternative names for PGLYRP1 / PGRPS antibody

Peptidoglycan recognition protein, PGRP-S, PGLYRP, PGRP, TNFSF3L

SwissProt ID

O75594 (Human), O88593 (Mouse), Q8SPP7 (Bovin), Q9JLN4 (Rat)

Gene ID

8993 (PGLYRP1), 21946 (Pglyrp1), 84387

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of PGLYRP1 / PGRPS antibody

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, thus, it is an excellent target for recognition by the eukaryotic inte immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-Ib) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood. PGRP-S is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. However, PGRP-S may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50-100 times higher than in neutrophils.

General readings

Lu X, Wang M, Qi J, Wang H, Li X, Gupta D, Dziarski R.
Peptidoglycan recognition proteins are a new class of human bactericidal proteins.
J Biol Chem. 2006 Mar 3;281(9):5895-907. Epub 2005 Dec 14.
PMID: 16354652

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PGLYRP1 / PGRPS (C-term) antibody

  Goat Anti-PGRP-S Antibody  
TA305756 (0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS antibody

  Mouse Monoclonal PGLYRP1/PGRP-S Antibody (188C424)  
Western Blot: PGRP Antibody (188C424) [TA336460] - Analysis using PGRP-S antibody. Lysate from human Jurkat cells probed with PGRP-S antibody at 2 ug/ml. Mouse IgG3 188C424 Purified Hu, Ms C, F, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS antibody

  Rabbit Polyclonal Anti-PGLYRP1 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Hela cells, K562 cells, human fetal liver tissue, Primary antibody: (PGLYRP1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS antibody

  Rabbit Polyclonal Anti-PGLYRP1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (PGLYRP1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PGLYRP1 / PGRPS (C-term) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Purified Can, Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PGLYRP1 - human gene knockout kit via CRISPR

PGLYRP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PGLYRP1 - human gene knockout kit via CRISPR

PGLYRP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PGLYRP1 - human gene knockout kit via CRISPR

PGLYRP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pglyrp1 - mouse gene knockout kit via CRISPR

Pglyrp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pglyrp1 - mouse gene knockout kit via CRISPR

Pglyrp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pglyrp1 - mouse gene knockout kit via CRISPR

Pglyrp1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PGLYRP1 / PGRPS

  Recombinant protein of human peptidoglycan recognition protein 1 (PGLYRP1)  
PGLYRP1 / PGRPS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PGLYRP1 overexpression lysate

PGLYRP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PGLYRP1 (mGFP-tagged) - Human peptidoglycan recognition protein 1 (PGLYRP1), 200 uL, >10^7 TU/mL

Lenti ORF particles, PGLYRP1 (mGFP-tagged) - Human peptidoglycan recognition protein 1 (PGLYRP1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, PGLYRP1 (Myc-DDK tagged) - Human peptidoglycan recognition protein 1 (PGLYRP1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PGLYRP1 (Myc-DDK tagged) - Human peptidoglycan recognition protein 1 (PGLYRP1) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pglyrp1 (GFP-tagged) - Mouse peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pglyrp1 (GFP-tagged) - Mouse peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pglyrp1 (Myc-DDK-tagged) - Mouse peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pglyrp1 (Myc-DDK-tagged) - Mouse peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pglyrp1 (GFP-tagged ORF) - Rat peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pglyrp1 (GFP-tagged ORF) - Rat peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pglyrp1 (Myc-DDK-tagged ORF) - Rat peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pglyrp1 (Myc-DDK-tagged ORF) - Rat peptidoglycan recognition protein 1 (Pglyrp1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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