PHC3 / EDR3 / PH3 antibody

Principal name

PHC3 / EDR3 / PH3 antibody

Alternative names for PHC3 / EDR3 / PH3 antibody

Polyhomeotic-like protein 3, hPH3, Early development regulatory protein 3, Homolog of polyhomeotic 3

SwissProt ID

Q8CHP6 (Mouse), Q8NDX5 (Human), Q9H9I4 (Human)

Gene ID

80012 (PHC3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PHC3 / EDR3 / PH3 antibody

Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptiol repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PHC3 / EDR3 / PH3 antibody

Western blot analysis of PHC3 in 3T3 cell lysate with PHC3 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PHC3 / EDR3 / PH3 antibody

Immunofluorescence of purified MaxPab antibody to PHC3 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

PHC3 / EDR3 / PH3 antibody

Western Blot: PHC3 Antibody [NB100-77312] - Detection of Human PHC3 by Western Blot and Immunoprecipitation.  Samples: Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-PHC3 antibody NB100-77312 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  PHC3 was also immunoprecipitated by another rabbit anti-PHC3 antibody, which recognizes a downstream epitope. Rabbit IgG Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

PHC3 / EDR3 / PH3 antibody

Western Blot: PHC3 Antibody [NB100-77313] - Detection of Human PHC3 by Western Blot of  Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells. Antibodies: Affinity purified  rabbit anti-PHC3 antibody NB100-77313 used for IP at 3 mcg/mg  lysate. PHC3 was also immunoprecipitated by rabbit anti-PHC3  antibody NB100-77312, which recognizes an upstream epitope.  Detection: Chemiluminescence  with an exposure time of 3 minutes. Rabbit IgG Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

PHC3 / EDR3 / PH3 antibody

Immunohistochemistry-Paraffin: PHC3 Antibody [NBP1-84896] - Immunohistochemical staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules and moderate nuclear staining in cells in glomeruli. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PHC3 / EDR3 / PH3

PHC3 / EDR3 / PH3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PHC3 / EDR3 / PH3

PHC3 / EDR3 / PH3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PHC3 293T Cell Transient Overexpression Lysate(Denatured)

PHC3 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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