Phosducin / PDC antibody

Principal name

Phosducin / PDC antibody

Alternative names for Phosducin / PDC antibody

PHD, PhLOP, MEKA, 33 kDa phototransducing protein

SwissProt ID

O77560 (Canfa), P19632 (Bovin), P20941 (Human), P20942 (Rat), P41686 (Felca), Q9QW08 (Mouse), Q9XS39 (Horse)

Gene ID

5132 (PDC), 20028 (Pdc)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse, Rat

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Phosducin / PDC antibody

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

General readings

Beetz, N., et al. J. Clin. Invest. 119(12):3597-3612(2009)
Klenk, C., et al. J. Biol. Chem. 281(13):8357-8364(2006)
Nishiguchi, K.M., et al. Mol. Vis. 10, 62-64 (2004)
Margulis, A., et al. Mol. Vis. 8, 477-482 (2002)
Wistow, G., et al. Mol. Vis. 8, 196-204 (2002)

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Phosducin / PDC (Center) antibody

Western blot analysis of Phosducin / PDC Antibody (Center) Cat.-No AP53227PU-N in CEM cell line lysates (35ug/lane). This demonstrates the PDC antibody detected the PDC protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Phosducin / PDC antibody

Phosducin / PDC Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

Phosducin / PDC antibody

Immunohistochemistry-Paraffin: Phosducin Antibody [NBP1-87773] - Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

3 Item(s)

per page
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