PI4K2A antibody

Principal name

PI4K2A antibody

Alternative names for PI4K2A antibody

Phosphatidylinositol 4-kinase type 2-alpha, Phosphatidylinositol 4-kinase type II-alpha

SwissProt ID

Q08B31 (Xenla), Q2TBE6 (Mouse), Q6PE18 (Danre), Q99M64 (Rat), Q9BTU6 (Human)

Gene ID

55361 (PI4K2A), 84095 (Pi4k2a), 114554

Available reactivities

Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of PI4K2A antibody

Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs. PI4K II is activated by detergent and inhibited by adenosine. Overexpression of PI4KII in COS-7 cells increases synthesis of PtdIns4P. Some cells overexpressing PI4KII have scattered or no perinuclear Golgi. Knockdown of PI4KII by RNA interference (RNAi) does not disrupt the Golgi, and some cells show expanded Golgi. RNAi reduces the Golgi level of PtdIns4P and blocks the association between AP1 and the trans-Golgi network. PI4KII RNAi had little effect on intra-Golgi trafficking, but it inhibited export to plasma membrane export by 35%. It has been proposed that PI4KII generates PtdIns4P-rich domains within the Golgi that specify docking of the AP1 coat machinery.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PI4K2A (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PI4K2A - human gene knockout kit via CRISPR

PI4K2A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PI4K2A - human gene knockout kit via CRISPR

PI4K2A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PI4K2A - human gene knockout kit via CRISPR

PI4K2A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PI4K2A - human gene knockout kit via CRISPR

PI4K2A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pi4k2a - mouse gene knockout kit via CRISPR

Pi4k2a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pi4k2a - mouse gene knockout kit via CRISPR

Pi4k2a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pi4k2a - mouse gene knockout kit via CRISPR

Pi4k2a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pi4k2a - mouse gene knockout kit via CRISPR

Pi4k2a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PI4K2A

  Recombinant protein of human phosphatidylinositol 4-kinase type 2 alpha (PI4K2A)  
PI4K2A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PI4K2A overexpression lysate

PI4K2A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PI4K2A (mGFP-tagged)-Human phosphatidylinositol 4-kinase type 2 alpha (PI4K2A), 200 uL, >10^7 TU/mL

Lenti ORF particles, PI4K2A (mGFP-tagged)-Human phosphatidylinositol 4-kinase type 2 alpha (PI4K2A), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pi4k2a (GFP-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pi4k2a (GFP-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pi4k2a (GFP-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pi4k2a (GFP-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pi4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pi4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pi4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pi4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL  
200 µl / €980.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pi4k2a (GFP-tagged ORF) - Rat phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pi4k2a (GFP-tagged ORF) - Rat phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL  
200 µl / €1,090.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pi4k2a (Myc-DDK-tagged ORF) - Rat phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pi4k2a (Myc-DDK-tagged ORF) - Rat phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL  
200 µl / €975.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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