PICALM antibody

Principal name

PICALM antibody

Alternative names for PICALM antibody

CALM, Phosphatidylinositol-binding clathrin assembly protein, Clathrin assembly lymphoid myeloid leukemia protein

SwissProt ID

Q13492 (Human)

Gene ID

8301 (PICALM), 3483019 (Q4L4T4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PICALM antibody

PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PICALM antibody

Western blot analysis of PICALM in EL4 cell lysate with PICALM antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PICALM (N-term) antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PICALM Control Peptide

PICALM
50 µg / €160.00
  Acris Antibodies GmbH

PICALM antibody

Western Blot analysis of PICALM expression in transfected 293T cell line (H00008301-T02) by PICALM MaxPab polyclonal antibody.

Lane 1: PICALM transfected lysate(67.1 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PICALM antibody

PICALM Rabbit Aff - Purified Hu E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

PICALM antibody

Immunohistochemistry-Paraffin: PICALM Antibody [NBP1-86658] - Immunohistochemical staining of human duodenum shows strong positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

PICALM antibody

Immunohistochemistry-Paraffin: PICALM Antibody [NBP1-86659] - Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PICALM (transcript variant 1)

PICALM Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PICALM

PICALM Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PICALM

PICALM Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PICALM 293T Cell Transient Overexpression Lysate(Denatured)

PICALM 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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