PILRA antibody

Principal name

PILRA antibody

Alternative names for PILRA antibody

PILR-alpha, FDF03, Paired immunoglobulin-like type 2 receptor alpha, Cell surface receptor FDF03, Inhibitory receptor PILR-alpha

SwissProt ID

Q2YFS3 (Mouse), Q9UKJ1 (Human), Q9UKJ1-4

Gene ID

29992 (PILRA), 231805 (Pilra)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Immunoprecipitation (IP)

Background of PILRA antibody

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.

General readings

Satoh,T., (2008) Cell 132 (6), 935-944

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PILRA antibody

  Rabbit Polyclonal Anti-PILRA Antibody  
WB Suggested Anti-PILRA Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Alexa Fluor 488 Hu F, ICC/IF
50 µg / €390.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Alexa Fluor 488 Hu F, ICC/IF
0.1 mg / €520.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Alexa Fluor 546 Hu F, ICC/IF
50 µg / €390.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Alexa Fluor 546 Hu ICC/IF
0.1 mg / €520.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Alexa Fluor 647 Hu F, ICC/IF
50 µg / €390.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Alexa Fluor 647 Hu F, ICC/IF
0.1 mg / €520.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Biotin Hu WB
50 µg / €360.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Biotin Hu WB
0.1 mg / €480.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Purified Hu F, IP, WB
50 µg / €330.00
  Dendritics SAS

PILRA antibody

WB analysis of treated-precipitates Rat IgG2a 36H2 Purified Hu F, IP, WB
0.1 mg / €440.00
  Dendritics SAS

CRISPR

Catalog No. Species Donor Vector  

PILRA - human gene knockout kit via CRISPR

PILRA - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PILRA - human gene knockout kit via CRISPR

PILRA - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PILRA - human gene knockout kit via CRISPR

PILRA - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PILRA - human gene knockout kit via CRISPR

PILRA - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pilra - mouse gene knockout kit via CRISPR

Pilra - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pilra - mouse gene knockout kit via CRISPR

Pilra - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pilra - mouse gene knockout kit via CRISPR

Pilra - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pilra - mouse gene knockout kit via CRISPR

Pilra - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PILRA overexpression lysate

PILRA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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