PILRB antibody

Principal name

PILRB antibody

Alternative names for PILRB antibody

PILR-beta, FDFACT, PP1551, Paired immunoglobulin-like type 2 receptor beta, Activating receptor PILR-beta, Cell surface receptor FDFACT

SwissProt ID

Q2YFS2 (Mouse), Q9UKJ0 (Human)

Gene ID

29990 (PILRB), 170741 (Pilrb1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of PILRB antibody

Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. Alternative splicing has been observed at this locus and three variants, encoding two distinct isoforms, are described. Additional transcript variants have been identified but their full-length nature has not been determined.

General readings

Wilson,M.D., (2006) Physiol. Genomics 27 (3), 201-218

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PILRB antibody

WB Suggested Anti-PILRB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Muscle Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PILRB antibody

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

PILRB antibody

Human Muscle; WB Suggested Anti-PILRB Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Muscle; PILRB antibody - middle region (ARP46949_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PILRB antibody

PILRB Goat Aff - Purified Hu E, P
50 µg / €480.00
  Novus Biologicals Inc.

PILRB antibody

Western Blot: PILRB Antibody [NBP1-69382] - This Anti-PILRB antibody was used in Western Blot of Fetal Muscle tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

PILRB antibody

Immunohistochemistry-Paraffin: PILRB Antibody [NBP1-84701] Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PILRB

PILRB Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PILRB

PILRB Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

PILRB

PILRB Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PILRB

PILRB Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PILRB 293T Cell Transient Overexpression Lysate(Denatured)

PILRB 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

11 Item(s)

per page
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