PINK1 antibody

Principal name

PINK1 antibody

Alternative names for PINK1 antibody

PTEN-induced putative kinase protein 1, PARK6, BRPK, PINK-1, Serine/threonine-protein kinase PINK1, mitochondrial, Parkinson disease (autosomal recessive) 6

SwissProt ID

Q961J3 (Drome), Q99MQ3 (Mouse), Q9BXM7 (Human)

Gene ID

65018 (PINK1), 68943 (Pink1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Hst (Hamster)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of PINK1 antibody

PINK1 (PTEN induced putative kinase 1) is a mitochondrial serine/threonine kinase which maintains mitochondrial function/integrity, provides protection against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins, and is involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). PINK1 is synthesized as a 63 kD protein which undergoes proteolyt processing to generate at least two cleaved forms (55 kD and 42 kD). PINK1 and its substrates have been found in the cytosol as well as in different sub-mitochondrial compartments, and according to the recent reports; PINK1 may be targeted to OMM (outer mitochondrial membrane) with its kinase domain facing the cytosol, providing a possible explanation for the observed physical interaction with the cytosolic E3 ubiquitin ligase Parkin. Defective PINK1 may cause alterations in processing, stability, localization and activity as well as binding to substrates/interaction-partners which ultimately leads to differential effects on mitochondrial function and morphology. Mutations in PINK1 are linked to autosomal recessive early onset Parkinson's disease, and are associated with loss of protective function, mitochondrial dysfunction, aggregation of alpha-synuclein, as well as proteasome dysfunction.

General readings

Chishti MA, Bohlega S, Ahmed M, Loualich A, Carroll P, Sato C, St George-Hyslop P, Westaway D, Rogaeva E.
T313M PINK1 mutation in an extended highly consanguineous Saudi family with early-onset Parkinson disease.
Arch Neurol. 2006 Oct;63(10):1483-5.
PMID: 17030667

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PINK1 antibody

Western blot analysis of anti-PINK1 Monoclonal Antibody (TA324354) in mouse brain tissue lysates. PINK1(arrow) was detected using the ascites Mab. (dilution 1:500) Mouse 38CT18.7 Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

TA303264 (1µg/ml) staining of Rat Testis lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

Western blot analysis of PINK1 expression in Jurkat cell lysate (Lane 1 & 2). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

Western Blot: PINK1 Antibody [TA336256] - Analysis of PINK1 in HeLA  whole cell lysate with and without treatment of 10 uM CCCP. Image courtesy of an anonymous customer review. Rabbit Purified Hu, Ms C, ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

Western Blot: PINK1 Antibody [TA336309] - Detection of murine PINK1 using TA336309. 1: molecular weight marker. 2. MES cell Mitochondria (20 ug). 3. MES cytosol (20 ug). 4. MES nuclear (20 ug) as negative control. 5. Purified human cytochrome C (0.1 ug) a Rabbit Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

Western Blot: PINK1 Antibody [TA336481] - Analysis of C-terminally V5His-tagged human PINK1 or N-teminally myc-tagged human PINK1 expressed in HEK293T cells using TA336481 at 1:1000 dilution. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

Immunohistochemistry-Paraffin: PINK1 Antibody [TA336796] - Stain in paraffin embedded mouse brain. Rabbit Purified Hu, Ms C, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

Western blot analysis of PINK1 in A431 cell lysate with PINK1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PINK1 antibody

Adult rat brain low-speed pellet immunoblot Mouse IgG1 N4/15 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

PINK1 antibody

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment) Mouse IgG1 N4/49 Supernatant Hu C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

PINK1 antibody

Adult rat brain low-speed pellet immunoblot Mouse IgG1 N4/15 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

PINK1 antibody

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment) Mouse IgG1 N4/49 Purified Hu C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

PINK1 antibody

Figure 1. Western blot analysis of PINK (arrow) using mouse monoclonal PINK antibody (Cat.#AM11055PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PINK gene (Lane 2). (Origene Technologies) Mouse IgG1 38CT20.8.5 Purified Hu WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

PINK1 (484-504) antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Bear, Bov, Bt, Can, Eq, Hst, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PINK1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu E, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PINK1 antibody

PINK1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PINK1 antibody

Western Blot analysis of PINK1 expression in transfected 293T cell line (H00065018-T02) by PINK1 MaxPab polyclonal antibody.

Lane 1: PINK1 transfected lysate(62.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PINK1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with PINK1 polyclonal antibody ( Cat # PAB4484 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma . Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

PINK1 antibody

PINK1 Rabbit Ms, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

PINK1 antibody

PINK1 Rabbit Ms, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

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