PITRM1 antibody

Principal name

PITRM1 antibody

Alternative names for PITRM1 antibody

Pitrilysin metalloproteinase 1, Metalloprotease 1, MP1, KIAA1104, Presequence protease mitochondrial

SwissProt ID

Q5JRX3 (Human), Q6PF24 (Xenla), Q7ZVZ6 (Danre), Q8K411 (Mouse), Q922N1 (Mouse), Q9BVJ5 (Human), Q9V9E3 (Drome)

Gene ID

10531 (PITRM1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PITRM1 antibody

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

General readings

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Pinho, C.M., et al. Neurosci. Lett. 469(2):204-208(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009)
Chow, K.M., et al. Biochemistry 48(13):2868-2877(2009)

10 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PITRM1 antibody

Host: Rabbit; Target Name: PITRM1; Sample Tissue: Thyroid Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PITRM1 (Center) antibody

Western blot analysis of PITRM1 Antibody (Center) Cat.-No AP53312PU-N in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the PITRM1 antibody detected the PITRM1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PITRM1 antibody

Western Blot analysis of PITRM1 expression in transfected 293T cell line (H00010531-T01) by PITRM1 MaxPab polyclonal antibody.

Lane 1: PITRM1 transfected lysate(114.07 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PITRM1 antibody

PITRM1 monoclonal antibody (M03), clone 1H3. Western Blot analysis of PITRM1 expression in A-431(Cat # L015V1 ). Mouse IgG2a 1H3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PITRM1 antibody

Immunohistochemistry-Paraffin: PITRM1 Antibody [NBP1-81728] - Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

PITRM1 antibody

Immunohistochemistry-Paraffin: PITRM1 Antibody [NBP1-81729] - Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PITRM1

PITRM1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PITRM1

PITRM1 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PITRM1 293T Cell Transient Overexpression Lysate(Denatured)

PITRM1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

PITRM1 overexpression lysate

PITRM1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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