PITX2 antibody

Principal name

PITX2 antibody

Alternative names for PITX2 antibody

Pituitary homeobox 2, ARP1, RGS, RIEG, RIEG1, Solurshin, ALL1-responsive protein ARP1, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor

SwissProt ID

O93385 (Chick), P97474 (Mouse), Q99697 (Human), Q9PWR3 (Xenla), Q9R0W1 (Rat), Q9W5Z2 (Danre)

Gene ID

5308 (PITX2), 18741 (Pitx2), 54284

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of PITX2 antibody

The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdomil organs. It also acts as a transcriptiol regulator involved in basal and hormone-regulated activity of prolactin. This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the termil differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdomil organs, and acts as a transcriptiol regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determition of left-right asymmetry during development. Altertively spliced transcript variants encoding distinct isoforms have been described.

General readings

Martin,D.M., et al., (2004) Dev. Biol. 267 (1), 93-108

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PITX2 (C-term) antibody

  Rabbit polyclonal PITX2 Antibody (C-term)  
Western blot analysis of anti-Pilx2 Pab (Cat.#TA324544) in CEM cell line lysates (35ug/lane). Pilx2(arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

PITX2 antibody

  Rabbit Polyclonal Anti-PITX2 Antibody  
WB Suggested Anti-PITX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: COLO205 cell lysatePITX2 is supported by BioGPS gene expression data to be expressed in COLO205 Rabbit IgG Purified Eq, GP, Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

PITX2 antibody

  Rabbit Polyclonal Anti-PITX2 Antibody  
WB Suggested Anti-PITX2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:31250; Positive Control: Human heart Rabbit IgG Purified Eq, Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

PITX2 antibody

  Rabbit Polyclonal Anti-PITX2 Antibody  
WB Suggested Anti-PITX2 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PITX2 antibody

  Rabbit Polyclonal Anti-PITX2 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-3: A375 cells, 293T cells, SKOV3 cells, Primary antibody: (PITX2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PITX2 - human gene knockout kit via CRISPR

PITX2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PITX2 - human gene knockout kit via CRISPR

PITX2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PITX2 - human gene knockout kit via CRISPR

PITX2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PITX2 - human gene knockout kit via CRISPR

PITX2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pitx2 - mouse gene knockout kit via CRISPR

Pitx2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pitx2 - mouse gene knockout kit via CRISPR

Pitx2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pitx2 - mouse gene knockout kit via CRISPR

Pitx2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pitx2 - mouse gene knockout kit via CRISPR

Pitx2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PITX2 (full length, N-term HIS tag, transcript variant 2)

  Recombinant protein of human paired-like homeodomain 2 (PITX2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
PITX2 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

PITX2 (full length, N-term HIS tag, transcript variant 1)

  Recombinant protein of human paired-like homeodomain 2 (PITX2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
PITX2 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PITX2 overexpression lysate

PITX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PITX2 overexpression lysate

PITX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PITX2 overexpression lysate

PITX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PITX2 (mGFP-tagged) - Human paired-like homeodomain 2 (PITX2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PITX2 (mGFP-tagged) - Human paired-like homeodomain 2 (PITX2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, PITX2 (mGFP-tagged) - Human paired-like homeodomain 2 (PITX2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PITX2 (mGFP-tagged) - Human paired-like homeodomain 2 (PITX2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

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