PIWIL2 antibody

Principal name

PIWIL2 antibody

Alternative names for PIWIL2 antibody

Piwi-like protein 2, PIWIL1L, HILI, Hiwi-like, Mili, Miwi-like, CT80, Cancer/testis antigen 80

SwissProt ID

A2CEI6 (Danre), Q8CDG1 (Mouse), Q8TC59 (Human)

Gene ID

55124 (PIWIL2), 57746 (Piwil2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of PIWIL2 antibody

PIWIL2 (UniProtKB/Swiss-Prot entry Q8TC59) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. It plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. PIWL2 acts via the piR metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRs and Piwi proteins and governs the methylation and subsequent repression of transposons. It directly binds piRs, a class of 24 to 30 nucleotide Rs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. PIWIL2 indirectly modulates expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Repression of PIWIL2 inhibits tumor cell growth.

General readings

Kuramochi-Miyagawa S, Kimura T, Yomogida K, et al. Two mouse piwi-related genes: miwi and mili. Mech. Dev. 108:121-33.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PIWIL2 antibody

  Rabbit anti-PIWIL2 polyclonal antibody  
Western blot analysis of fetal testis lysates with anti-PIWIL2 antibody (1:400). Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PIWIL2 (Center) antibody

  Rabbit Polyclonal PIWI-L2 Antibody  
Western blot analysis of PIWI-L2 in HepG2 cell lysate with PIWI-L1 antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PIWIL2 (Center) antibody

  Rabbit Polyclonal PIWI-L2 Antibody  
Immunohistochemistry of PIWI-L2 in human brain tissue with PIWI-L2 antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

PIWIL2 antibody

  Anti-PIWIL2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon and ovarian cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PIWIL2 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PIWIL2 antibody

  Rabbit Polyclonal Anti-PIWIL2 Antibody  
WB Suggested Anti-PIWIL2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Small Intestine Rabbit IgG Purified Bov, Can, Eq, GP, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PIWIL2 antibody

  Rabbit Polyclonal PIWIL2 Antibody  
Determination of the antibody titer To determine the titer of the antibody, an ELISA was performed using a serial dilution of the antibody against PIWIL2. The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 1), the titer of the antibody was estimated to be 1:2,750. Rabbit IgG Purified Hu, Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

PIWIL2 antibody

PIWIL2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PIWIL2 antibody

PIWIL2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PIWIL2 antibody

Immunoblot analysis of mouse testis tissue lysate. Mouse IgG1 11C11 Purified Hu E, IP, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

PIWIL2 antibody

Human Small Intestine; WB Suggested Anti-PIWIL2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Small Intestine; PIWIL2 Antibody (ARP57108_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

PIWIL2 - human gene knockout kit via CRISPR

PIWIL2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PIWIL2 - human gene knockout kit via CRISPR

PIWIL2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PIWIL2 - human gene knockout kit via CRISPR

PIWIL2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PIWIL2 - human gene knockout kit via CRISPR

PIWIL2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PIWIL2 (mGFP-tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PIWIL2 (mGFP-tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PIWIL2 (mGFP-tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PIWIL2 (mGFP-tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PIWIL2 (Myc-DDK tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PIWIL2 (Myc-DDK tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, PIWIL2 (Myc-DDK tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PIWIL2 (Myc-DDK tagged) - Human piwi-like 2 (Drosophila) (PIWIL2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Piwil2 (GFP-tagged) - Mouse piwi-like homolog 2 (Drosophila) (Piwil2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Piwil2 (GFP-tagged) - Mouse piwi-like homolog 2 (Drosophila) (Piwil2), 200 uL, >10^7 TU/mL  
200 µl / €1,740.00
  OriGene Technologies, Inc.

Lenti ORF particles, Piwil2 (Myc-DDK-tagged) - Mouse piwi-like homolog 2 (Drosophila) (Piwil2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Piwil2 (Myc-DDK-tagged) - Mouse piwi-like homolog 2 (Drosophila) (Piwil2), 200 uL, >10^7 TU/mL  
200 µl / €1,570.00
  OriGene Technologies, Inc.

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