PKN2 antibody

Principal name

PKN2 antibody

Alternative names for PKN2 antibody

PRK2, PRKCL2, Protein kinase C-like 2, Serine/threonine-protein kinase N2, Protein-kinase C-related kinase 2

SwissProt ID

O08874 (Rat), Q16513 (Human), Q8BWW9 (Mouse)

Gene ID

5586 (PKN2), 109333 (Pkn2)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PKN2 antibody

Pkn2 is a PKC-related serine/threonine-protein kise and Rho/Rac effector protein that participates in specific sigl transduction responses in the cell. It plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation sigling processes. Pkn2 phosphorylates CTTN in hyaluron-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin, phosphorylates HDAC5, therefore lead to impair HDAC5 import. It is a direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells and is required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. It stimulates FYN kise activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation, regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion, inhibits Akt pro-survival-induced kise activity. It mediates Rho protein-induced transcriptiol activation via the c-fos serum response factor (SRF).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PKN2 antibody

Immunohistochemical analysis of paraffin-embedded prostate tissues using PRK2 mouse mAb with DAB staining. Mouse IgG1 1D1 Ascites Hu, Mky, Ms, Rt E, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

PKN2 antibody

  Rabbit polyclonal antibody to protein kinase N2 (protein kinase N2)  
Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308478 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PKN2 antibody

  Rabbit Polyclonal Anti-PKN2 Antibody  
Host: Rabbit; Target Name: Pkn2; Sample Tissue: Mouse Thymus lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PKN2 - human gene knockout kit via CRISPR

PKN2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PKN2 - human gene knockout kit via CRISPR

PKN2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PKN2 - human gene knockout kit via CRISPR

PKN2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PKN2 - human gene knockout kit via CRISPR

PKN2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pkn2 - mouse gene knockout kit via CRISPR

Pkn2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pkn2 - mouse gene knockout kit via CRISPR

Pkn2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pkn2 - mouse gene knockout kit via CRISPR

Pkn2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pkn2 - mouse gene knockout kit via CRISPR

Pkn2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PKN2

  Recombinant protein of human protein kinase N2 (PKN2)  
PKN2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PKN2 overexpression lysate

PKN2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pkn2 (GFP-tagged) - Mouse protein kinase N2 (cDNA clone MGC:62484 IMAGE:6400440), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pkn2 (GFP-tagged) - Mouse protein kinase N2 (cDNA clone MGC:62484 IMAGE:6400440), 200 uL, >10^7 TU/mL  
200 µl / €1,390.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pkn2 (GFP-tagged) - Mouse protein kinase N2 (Pkn2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pkn2 (GFP-tagged) - Mouse protein kinase N2 (Pkn2), 200 uL, >10^7 TU/mL  
200 µl / €1,760.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pkn2 (Myc-DDK-tagged) - Mouse protein kinase N2 (cDNA clone MGC:62484 IMAGE:6400440), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pkn2 (Myc-DDK-tagged) - Mouse protein kinase N2 (cDNA clone MGC:62484 IMAGE:6400440), 200 uL, >10^7 TU/mL  
200 µl / €1,250.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pkn2 (Myc-DDK-tagged) - Mouse protein kinase N2 (Pkn2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pkn2 (Myc-DDK-tagged) - Mouse protein kinase N2 (Pkn2), 200 uL, >10^7 TU/mL  
200 µl / €1,580.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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