PKN2 antibody

Principal name

PKN2 antibody

Alternative names for PKN2 antibody

PRK2, PRKCL2, Protein kinase C-like 2, Serine/threonine-protein kinase N2, Protein-kinase C-related kinase 2

SwissProt ID

O08874 (Rat), Q16513 (Human), Q8BWW9 (Mouse)

Gene ID

5586 (PKN2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C)

Background of PKN2 antibody

Pkn2 is a PKC-related serine/threonine-protein kise and Rho/Rac effector protein that participates in specific sigl transduction responses in the cell. It plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation sigling processes. Pkn2 phosphorylates CTTN in hyaluron-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin, phosphorylates HDAC5, therefore lead to impair HDAC5 import. It is a direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells and is required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. It stimulates FYN kise activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation, regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion, inhibits Akt pro-survival-induced kise activity. It mediates Rho protein-induced transcriptiol activation via the c-fos serum response factor (SRF).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PKN2 antibody

Immunohistochemical analysis of paraffin-embedded prostate tissues using PRK2 mouse mAb with DAB staining. Mouse IgG1 1D1 Ascites Hu, Mky, Ms, Rt E, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

PKN2 antibody

Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308478 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PKN2 antibody

Host: Rabbit; Target Name: Pkn2; Sample Tissue: Mouse Thymus lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PKN2 antibody

Detection limit for recombinant GST tagged PKN2 is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 3A7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PKN2 (C-term) antibody

Human HEK293T; WB Suggested Anti-PKN2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: 293T Whole Cell. PKN2 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells.; PKN2 antibody - C-terminal region (ARP61894_P050) in Human HEK293T cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PKN2 antibody

Immunohistochemistry: PRK2 Antibody (E352) [NB110-57437] - Immunohistochemical analysis of paraffin-embedded human colon carcinoma using anti-PRK2 (catalog #110-57437). Rabbit IgG E352 Hu, Ms, Rt F, ICC/IF, IP, P, WB
0.1 ml / €480.00
  Novus Biologicals Inc.

PKN2 antibody

WB and IP: PKN2 Antibody [NBP1-30086] - Whole cell lysate from HeLa and 293T cells. PKN2 was also immunoprecipitated by rabbit anti-PKN2 antibody NBP1-30084. For blotting IPed PKN2, the ReliaBLOT®  Reagents and Procedures were used. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

PKN2 antibody

Immunofluorescence: PKN2 Antibody [NBP1-31367] - Immunofluorescence analysis of HeLa, using NBP1-31367 at 1:200 dilution. Rabbit IgG Hu ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PKN2

PKN2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PKN2

PKN2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PKN2

PKN2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

PKN2

PKN2 Human
5 µg / €520.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PKN2 overexpression lysate

PKN2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

13 Item(s)

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