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PLA1A antibody

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Principal name

PLA1A antibody

Alternative names for PLA1A antibody

NMD, PSPLA1, Phospholipase A1 member A

SwissProt ID

P97535 (Rat), Q53H76 (Human), Q5E9H0 (Bovin), Q6NYZ4 (Danre), Q8VI78 (Mouse)

Gene ID

51365 (PLA1A), 85031 (Pla1a)

Ncbi ID

NP_001193889, NP_056984, NP_001193889.1, 9606, NP_056984.1, NM_015900, NP_598863.3, NM_134102

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PLA1A antibody

PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.

General readings

Morikawa, R.K., et al. J. Biol. Chem. 284(39):26620-26630(2009)
Aoki, J., et al. Biochim. Biophys. Acta 1582 (1-3), 26-32 (2002)
Wang, J., et al. J. Hum. Genet. 47(11):611-613(2002)
Nagai, Y., et al. J. Biol. Chem. 274(16):11053-11059(1999)
van Groningen, J.J., et al. FEBS Lett. 404(1):82-86(1997)

AP53321PU-N - PLA1A
Western blot analysis of PLA1A Antibody (Center) Cat.-No AP53321PU-N in mouse liver tissue and CEM cell line lysates (35ug/lane). This demonstrates the PLA1A antibody detected the PLA1A protein (arrow).
ARP46235_P050 - PLA1A
Human 293T; WB Suggested Anti-PLA1A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 293T cell lysate; PLA1A antibody - middle region (ARP46235_P050) in Human 293T cells using Western Blot
C17709-1 - PLA1A
Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is treated with the synthesized peptide.
H00051365-B01 - PLA1A
Western Blot analysis of PLA1A expression in transfected 293T cell line (H00051365-T01) by PLA1A MaxPab polyclonal antibody.Lane 1: PLA1A transfected lysate(50.16 KDa).Lane 2: Non-transfected lysate.
H00051365-B01P - PLA1A
Western Blot analysis of PLA1A expression in transfected 293T cell line (H00051365-T01) by PLA1A MaxPab polyclonal antibody.Lane 1: PLA1A transfected lysate(50.16 KDa).Lane 2: Non-transfected lysate.
AR51481PU-N - PLA1A
TA319922 - PLA1A
Western blot analysis of PLA1A in human kidney tissue lysate with PLA1A antibody at (A) 1 and (B) 2 ug/mL.
TA319922 - PLA1A
Immunofluorescence of PLA1A in human kidney tissue with PLA1A antibody at 20 ug/mL.
TA339332 - PLA1A
WB Suggested Anti-PLA1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysate

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLA1A (C-term) antibody
  Rabbit Polyclonal PLA1A Antibody  
Western blot analysis of PLA1A in human kidney tissue lysate with PLA1A antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Rt E, ICC/IF, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.
+1 additional image

PLA1A antibody
  Rabbit Polyclonal Anti-PLA1A Antibody  
WB Suggested Anti-PLA1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €360.00
  OriGene Technologies, Inc.

PLA1A (Center) antibody
Western blot analysis of PLA1A Antibody (Center) Cat.-No AP53321PU-N in mouse liver tissue and CEM cell line lysates (35ug/lane). This demonstrates the PLA1A antibody detected the PLA1A protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PLA1A antibody
Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
50 µg / €230.00
  Assay Biotech

PLA1A antibody
Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PLA1A - human gene knockout kit via CRISPR
PLA1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLA1A - human gene knockout kit via CRISPR
PLA1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLA1A - human gene knockout kit via CRISPR
PLA1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLA1A - human gene knockout kit via CRISPR
PLA1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR
Pla1a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR
Pla1a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR
Pla1a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR
Pla1a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PLA1A (26-456, His-tag)
PLA1A Human Purified > 80 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PLA1A (26-456, His-tag)
PLA1A Human Purified > 80 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

PLA1A overexpression lysate
PLA1A overexpression lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PLA1A (mGFP-tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, PLA1A (mGFP-tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,092.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, PLA1A (Myc-DDK tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1 , 200 uL, >10^7 TU/mL
Lenti ORF particles, PLA1A (Myc-DDK tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €979.00
  OriGene Technologies, Inc.
 

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pla1a (GFP-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL
Lenti ORF particles, Pla1a (GFP-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL  
200 µl / €1,092.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Pla1a (Myc-DDK-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL
Lenti ORF particles, Pla1a (Myc-DDK-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL  
200 µl / €979.00
  OriGene Technologies, Inc.
 

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Available Filters

Product Type
  1. CRISPR (8)
  2. Human Lenti ORF Particle (2)
  3. Lysate (1)
  4. Mouse Lenti ORF Particle (2)
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  6. Protein | Growth Factor (2)
Clonality
  1. Polyclonal (5)
Target
  1. PLA1A (7)
Property
  1. C-term (1)
  2. Center (1)
Reactivity
  1. Human (Hu) (5)
  2. Mouse (Ms) (2)
  3. Rat (Rt) (2)
  4. Bovine (Bov) (1)
  5. Canine (Can) (1)
  6. Equine (Eq) (1)
  7. Guinea Pig (GP) (1)
  8. Porcine (Por) (1)
  9. Rabbit (Rb) (1)
  10. Zebrafish (Ze) (1)
Applications
  1. Enzyme Immunoassay (E) (3)
  2. Western blot / Immunoblot (WB) (3)
  3. Paraffin Sections (P) (2)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Aff - Purified (4)
  2. Purified (3)
Host
  1. Rabbit (5)
Images
  1. 1 image (7)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Paraffin Sections (P) (2)
  3. Immunofluorescence (IF) (1)
Species (Protein)
  1. Human (2)
Source
  1. E. coli (2)
Species (CRISPR)
  1. Human (4)
  2. Mouse (4)
Donor Vector
  1. GFP-Puro (2)
  2. Luciferase-Puro (2)
  3. RFP-BSD (2)
  4. mBFP-Neo (2)
Manufacturer
  1. Acris - OriGene (18)
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