PLA1A antibody
Principal name
PLA1A antibody
Alternative names for PLA1A antibody
NMD, PSPLA1, Phospholipase A1 member A
Ncbi ID
NP_001193889, NP_056984, NP_001193889.1, 9606, NP_056984.1, NM_015900, NP_598863.3, NM_134102
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of PLA1A antibody
PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.
General readings
Morikawa, R.K., et al. J. Biol. Chem. 284(39):26620-26630(2009)
Aoki, J., et al. Biochim. Biophys. Acta 1582 (1-3), 26-32 (2002)
Wang, J., et al. J. Hum. Genet. 47(11):611-613(2002)
Nagai, Y., et al. J. Biol. Chem. 274(16):11053-11059(1999)
van Groningen, J.J., et al. FEBS Lett. 404(1):82-86(1997)





Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA319922 | PLA1A (C-term) antibody |
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Rabbit Polyclonal PLA1A Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Rt | E, ICC/IF, WB |
0.1 mg /
€371.00
|
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OriGene Technologies, Inc. | |||||||
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TA339332 | PLA1A antibody |
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Rabbit Polyclonal Anti-PLA1A Antibody | |||||||
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Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze | WB |
50 µg /
€360.00
|
|
OriGene Technologies, Inc. | |||||||
AP53321PU-N | PLA1A (Center) antibody |
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Rabbit | Ig | Aff - Purified | Hu, Ms | WB |
0.4 ml /
€370.00
|
|
Acris Antibodies GmbH | |||||||
C17709-1 | PLA1A antibody |
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Rabbit | Aff - Purified | Hu | E, P |
50 µg /
€230.00
|
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Assay Biotech | |||||||
C17709-2 | PLA1A antibody |
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Rabbit | Aff - Purified | Hu | E, P |
0.1 mg /
€330.00
|
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Assay Biotech |
CRISPR
Catalog No. | Species | Donor Vector | |
---|---|---|---|
KN219486 | PLA1A - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN219486BN | PLA1A - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN219486LP | PLA1A - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN219486RB | PLA1A - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN313375 | Pla1a - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN313375BN | Pla1a - mouse gene knockout kit via CRISPR |
||
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Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN313375LP | Pla1a - mouse gene knockout kit via CRISPR |
||
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Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN313375RB | Pla1a - mouse gene knockout kit via CRISPR |
||
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Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Proteins & Growth Factors
Catalog No. | Species | Pres. | Purity | Source | |
---|---|---|---|---|---|
AR51481PU-N | PLA1A (26-456, His-tag) |
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Human | Purified | > 80 % by SDS - PAGE | E. coli |
0.5 mg /
€730.00
|
Acris Antibodies GmbH | |||||
AR51481PU-S | PLA1A (26-456, His-tag) |
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Human | Purified | > 80 % by SDS - PAGE | E. coli |
0.1 mg /
€300.00
|
Acris Antibodies GmbH |
Lysates
Catalog No. | ||
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LY414332 | PLA1A overexpression lysate |
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0.1 mg /
€495.00
|
|
OriGene Technologies, Inc. |
Human Lenti ORF Particles
Catalog No. | ||
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RC219486L2V | Lenti ORF particles, PLA1A (mGFP-tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1, 200 uL, >10^7 TU/mL |
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200 µl /
€1,092.00
|
|
OriGene Technologies, Inc. | ||
RC219486L1V | Lenti ORF particles, PLA1A (Myc-DDK tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1 , 200 uL, >10^7 TU/mL |
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200 µl /
€979.00
|
|
OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
Catalog No. | ||
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MR207283L2V | Lenti ORF particles, Pla1a (GFP-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL |
|
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200 µl /
€1,092.00
|
|
OriGene Technologies, Inc. | ||
MR207283L1V | Lenti ORF particles, Pla1a (Myc-DDK-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL |
|
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200 µl /
€979.00
|
|
OriGene Technologies, Inc. | ||