PLA1A antibody

Principal name

PLA1A antibody

Alternative names for PLA1A antibody

NMD, PSPLA1, Phospholipase A1 member A

SwissProt ID

P97535 (Rat), Q53H76 (Human), Q5E9H0 (Bovin), Q6NYZ4 (Danre), Q8VI78 (Mouse)

Gene ID

51365 (PLA1A), 85031 (Pla1a)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PLA1A antibody

PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.

General readings

Morikawa, R.K., et al. J. Biol. Chem. 284(39):26620-26630(2009)
Aoki, J., et al. Biochim. Biophys. Acta 1582 (1-3), 26-32 (2002)
Wang, J., et al. J. Hum. Genet. 47(11):611-613(2002)
Nagai, Y., et al. J. Biol. Chem. 274(16):11053-11059(1999)
van Groningen, J.J., et al. FEBS Lett. 404(1):82-86(1997)

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLA1A (C-term) antibody

  Rabbit Polyclonal PLA1A Antibody  
Western blot analysis of PLA1A in human kidney tissue lysate with PLA1A antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PLA1A antibody

  Rabbit Polyclonal Anti-PLA1A Antibody  
WB Suggested Anti-PLA1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PLA1A (Center) antibody

Western blot analysis of PLA1A Antibody (Center) Cat.-No AP53321PU-N in mouse liver tissue and CEM cell line lysates (35ug/lane). This demonstrates the PLA1A antibody detected the PLA1A protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PLA1A antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
50 µg / €230.00
  Assay Biotech

PLA1A antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PLA1A - human gene knockout kit via CRISPR

PLA1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PLA1A - human gene knockout kit via CRISPR

PLA1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLA1A - human gene knockout kit via CRISPR

PLA1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLA1A - human gene knockout kit via CRISPR

PLA1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR

Pla1a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR

Pla1a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR

Pla1a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pla1a - mouse gene knockout kit via CRISPR

Pla1a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PLA1A (26-456, His-tag)

PLA1A Human Purified > 80 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PLA1A (26-456, His-tag)

PLA1A Human Purified > 80 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

PLA1A overexpression lysate

PLA1A overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PLA1A (mGFP-tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PLA1A (mGFP-tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.

Lenti ORF particles, PLA1A (Myc-DDK tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PLA1A (Myc-DDK tagged) - Human phospholipase A1 member A (PLA1A), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €950.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pla1a (GFP-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pla1a (GFP-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.

Lenti ORF particles, Pla1a (Myc-DDK-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pla1a (Myc-DDK-tagged) - Mouse phospholipase A1 member A (Pla1a), 200 uL, >10^7 TU/mL  
200 µl / €950.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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