Plakophilin 1 / PKP1 antibody

Principal name

Plakophilin 1 / PKP1 antibody

Alternative names for Plakophilin 1 / PKP1 antibody

Plakophilin-1, Band 6 protein, B6P

SwissProt ID

P97350 (Mouse), Q13835 (Human), Q28161 (Bovin)

Gene ID

5317 (PKP1), 18772 (Pkp1)

Available reactivities

Bov (Bovine), Chk (Chicken), Hu (Human), Por (Porcine), Xen (Xenopus), Ms (Mouse)

Available hosts

Mouse, Guinea Pig

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of Plakophilin 1 / PKP1 antibody

Kit Component:
- KN216972G1, PKP1 gRNA vector 1 in pCas-Guide vector
- KN216972G2, PKP1 gRNA vector 2 in pCas-Guide vector
- KN216972D, donor vector containing left and right homologous arms and Luciferase-Puro functional cassette
- GE100003, scramble sequence in pCas-Guide vector
CRISPR Manual:
CRISPR/CAS9 Genome Editing Manual

General readings

1. Schmidt A, Langbein L, Rode M, Prätzel S, Zimbelmann R, Franke WW. Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components. Cell Tissue Res. 1997 Dec;290(3):481-99. PubMed PMID: 9369526. 
2. Yang C, Fischer-Kešo R, Schlechter T, Ströbel P, Marx A, Hofmann I: Plakophilin 1-deficient cells upregulate SPOCK1: implications for prostate cancer progression. Tumor Biol. (2015) DOI 10.1007/s13277-015-3628-3.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Plakophilin 1 / PKP1 antibody

Plakophilin 1 / PKP1 Guinea Pig Serum Bov, Hu, Ms, Xen C, ICC/IF, P, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

Plakophilin 1 / PKP1 antibody

Plakophilin 1 / PKP1 Mouse IgG1 PP1-2D6 Supernatant Bov, Chk, Hu, Por C, E, WB
5 ml / €280.00
  Acris Antibodies GmbH

Plakophilin 1 / PKP1 antibody

Plakophilin 1 / PKP1 Mouse IgG1 PP1-5C2 Supernatant Bov, Hu, Por, Xen C, E, ICC/IF, P, WB
5 ml / €280.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PKP1 - human gene knockout kit via CRISPR

PKP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PKP1 - human gene knockout kit via CRISPR

PKP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PKP1 - human gene knockout kit via CRISPR

PKP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PKP1 - human gene knockout kit via CRISPR

PKP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pkp1 - mouse gene knockout kit via CRISPR

Pkp1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pkp1 - mouse gene knockout kit via CRISPR

Pkp1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Plakophilin 1 / PKP1 (transcript variant 1a)

  Recombinant protein of human plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (PKP1), transcript variant 1a  
Plakophilin 1 / PKP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PKP1 (mGFP-tagged) - Human plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (PKP1), transcript variant 1a, 200 uL, >10^7 TU/mL

Lenti ORF particles, PKP1 (mGFP-tagged) - Human plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (PKP1), transcript variant 1a, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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