Plakophilin-2 antibody

Principal name

Plakophilin-2 antibody

Alternative names for Plakophilin-2 antibody

PKP2

SwissProt ID

Q99959 (Human), Q9CQ73 (Mouse)

Gene ID

5318 (PKP2), 67451

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Xen (Xenopus), Rt (Rat), Eq (Equine)

Available hosts

Mouse, Rabbit, Guinea Pig, Goat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of Plakophilin-2 antibody

Plakophilin-2 (PKP2) is a member of the Armadillo/β-catenin family. It contains eight ARM repeats and can exist in two slice isoforms (2a and 2b). Plakophilin-2 is highly abundant in simple and stratified epithelial cells; but is also expressed in non-epithelial cells, such as the myocardium and lymph node follicles. In epithelial cells, it is localized to desmosomal plaques and plays an important role in cell-cell adhesion processes. Plakophilin-2 also maintains the cell-cell junctions of cardiac tissue, and is essential for proper cardiac function. Mutations in the plakophilin-2 gene cause arrhythmogenic right ventricular cardiomyopathy 9, a condition characterized by partial breakdown of the myocardium of the right ventricle, electrical instability, and sudden death. Plakophilin-2 has also been implicated in the development of cancer.

General readings

Fressart, V., et al. Europace 12(6):861-868(2010)
Cox, M.G., et al. Circ Arrhythm Electrophysiol 3(2):126-133(2010)
Christensen, A.H., et al. Cardiology 115(2):148-154(2010)
den Haan, A.D., et al. Circ Cardiovasc Genet 2(5):428-435(2009)
Bhuiyan, Z.A., et al. Circ Cardiovasc Genet 2(5):418-427(2009)

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Plakophilin-2 (125-139) antibody

(0.3ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Plakophilin-2 antibody

Western blot analysis of extracts of various cell lines, using PKP2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Plakophilin-2 antibody

WB Suggested Anti-PKP2 Antibody ; Positive Control: Lane1-4: 20ug mouse keratinocyte lysate; Primary Antibody Dilution : 1:1000; Secondary Antibody : Anti-rabbit-HRP; Secondry Antibody Dilution : 1:6000; Rabbit IgG Purified Bov, Can, Eq, Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

Plakophilin-2 (527-872) antibody

Plakophilin-2 Mouse IgG1 Pkp2-518 Supernatant Bov, Hu, Ms, Ovine, Rt C, P, WB
5 ml / €300.00
  Acris Antibodies GmbH

Plakophilin-2 antibody

Western blot (WB) analysis of Plakophilin 2 antibody (Cat.-No.: AP01493PU-N)  in extracts from HeLa cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Plakophilin-2 (C-term) antibody

Plakophilin-2 Guinea Pig Serum Bov, Hu, Ms, Ovine, Rt C, ICC/IF, P, WB
0.1 ml / €370.00
  Acris Antibodies GmbH

Plakophilin-2 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue reacte with Plakophilin-2 Antibody (C-term) Cat.-No AP53319PU-N, whcih was peroxidase conjugated to the secondary antibody and followed by DAB staining.This data demonstrates the use of PKP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Plakophilin-2 antibody

Plakophilin-2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Plakophilin-2 antibody

Western blot analysis of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Plakophilin-2 antibody

Western blot analysis of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Plakophilin-2 antibody

mouse keratinocyte; WB Suggested Anti-PKP2 Antibody . . Positive Control: Lane1-4: 20ug mouse keratinocyte lysate. Primary Antibody Dilution : 1:1000. Secondary Antibody : Anti-rabbit-HRP . Secondry Antibody Dilution : 1:6000. Submitted by: Jiangli Chen and Peter Koch, University of Colorado Denver; PKP2 antibody - N-terminal region (ARP56587_P050) in mouse keratinocyte cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Plakophilin-2 antibody

Plakophilin 2 Antibody [8H6] Mouse IgG1 8H6 Purified Hu, Ms IP, P, WB
0.1 ml / €400.00
  Immuquest

Plakophilin-2 antibody

Plakophilin-2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Plakophilin-2 antibody

Plakophilin-2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Plakophilin-2 antibody

Plakophilin-2 Goat Aff - Purified Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Plakophilin-2 antibody

Immunohistochemistry-Paraffin: Plakophilin 2 Antibody [NBP1-86078] - Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Plakophilin 2a/b / PKP2a/b antibody

Plakophilin 2a/b / PKP2a/b Mouse IgG1 PP2/62 + PP2/86 + PP2/150 Supernatant Bov, Can, Hu, Ms, Xen C, IP, P, WB
5 ml / €270.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

PKP2 overexpression lysate

PKP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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