Plasminogen / PLG antibody

Principal name

Plasminogen / PLG antibody

SwissProt ID

P00747 (Human), P06867 (Pig), P06868 (Bovin), P20918 (Mouse), P80009 (Canfa), P80010 (Horse), P81286 (Sheep), Q01177 (Rat)

Gene ID

5340 (PLG), 18815 (Plg), 85253, 280897, 733660

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Fe (Feline), GP (Guinea Pig), Chk (Chicken), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat, Sheep, Rat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (capture) (E(capture)), Paraffin Sections (P), ELISA (detection) (E(detection)), Radioimmunoassay (R), Immunoprecipitation (IP), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunodiffusion (ID), Dot blot (Dot), Flow Cytometry (F)

Background of Plasminogen / PLG antibody

Plasmin is an enzyme formed in the circulating blood, and many other extracellular fluids, from the zymogen plasminogen. Plasminogen is a single-chain glycoprotein with 790 amino acid residues. Activation to the active form, plasmin, by urokinase involves cleavage at the arg-val bond between residues 560 and 561, resulting in the formation of the 2-chain plasmin molecule held together by 2 disulfide linkages. The heavier chain contains about 411 residues and the lighter chain about 233. The main function of plasmin is the digestion of fibrin in blood clots. Plasmin is a proteolytic enzyme with a specificity similar to that of trypsin. Like trypsin, plasmin belongs to the family of serine proteinases, in which the active site catalytic triad, his-57, asp-102, and ser-195 (chymotrypsin numbering), is situated in the light chain.
Plasmin acts as a proteolytic factor in a variety of processes other than fibrinolysis; including embryonic development, tissue remodelling, tumour invasion and inflammation; in ovulation it weakens the walls of the Graafian follicle. A Deficiency of plasmin may lead to thrombosis, as clots are not degraded adequately.

General readings

General / background references:Sim BK et al. Angiostatin and endostatin: endogenous inhibitors of tumor growth. Cancer Metastasis Rev 19:181-90 (2000). PubMed PMID: 11191058
Drixler TA et al. Angiogenesis and surgery: from mice to man. Eur J Surg 166:435-46 (2000). PubMed PMID: 10890539

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Angiostatin antibody

Angiostatin Rabbit Aff - Purified Hu E, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Angiostatin antibody

Angiostatin Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Plasminogen / PLG antibody

Goat anti Plasminogen antibody (200-101-208 lot 6571) was used to detect Plasminogen under reducing (R) and non-reducing (NR) conditions. Reduced samples of purified target proteins contained 4% BME and were boiled for 5 minutes. Samples of ~1ug of protein per lane were run by SDS-PAGE. Protein was transferred to nitrocellulose and probed with 1:3000 dilution of primary antibody (ON 4 C in MB-070). Detection shown was using Dylight 649 conjugated Donkey anti goat. Goat Serum Hu E, IP, WB
2 ml / €900.00
  OriGene Technologies, Inc.

Plasminogen / PLG antibody

Goat anti Plasminogen antibody (200-101-208 lot 6571) was used to detect Plasminogen under reducing (R) and non-reducing (NR) conditions. Reduced samples of purified target proteins contained 4% BME and were boiled for 5 minutes. Samples of ~1ug of protein per lane were run by SDS-PAGE. Protein was transferred to nitrocellulose and probed with 1:3000 dilution of primary antibody (ON 4 C in MB-070). Detection shown was using Dylight 649 conjugated Donkey anti goat. Goat Purified Hu E, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Plasminogen / PLG antibody

Plasminogen / PLG Sheep FITC Hu ICC/IF
1 ml / €340.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Goat Biotin Hu E, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Goat HRP Hu C, E, IP, P, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Western blot analysis of extracts from 293 cells, using PLMN (heavy chain A short form, Cleaved-Val98) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Plasminogen / PLG antibody

Western blot analysis of extracts from Jurkat cells, using PLG antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Plasminogen / PLG antibody

Western blot analysis of PLG antibody (C-term) (Cat.#TA324919) in K562 cell line lysates (35ug/lane). PLG (arrow) was detected using the purified Pab. Rabbit IgG Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Plasminogen / PLG antibody

WB Suggested Anti-PLG Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: PANC1 cell lysate PLG is supported by BioGPS gene expression data to be expressed in PANC1 Rabbit IgG Purified Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Plasminogen / PLG antibody

Plasminogen / PLG Mouse IgG1 B412M Purified Hu E, P
1 mg / €520.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Rabbit IgG Purified Hu ID, WB
1 ml / €320.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Rabbit IgG Azide Free Hu Dot, E, ICC/IF, ID, IP, R, WB
10 mg / €230.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Rabbit IgG Biotin Hu Dot, E, ICC/IF, ID, IP, R, WB
1 ml / €340.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Rabbit IgG Aff - Purified Hu Dot, E, ICC/IF, ID, IP, R, WB
1 mg / €430.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Goat Serum Hu ID, IP, R
1 ml / €250.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Rabbit Serum Hu ID, IP
1 ml / €250.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

Plasminogen / PLG Sheep HRP Hu C, E
1 ml / €410.00
  Acris Antibodies GmbH

Plasminogen / PLG antibody

PLG MaxPab polyclonal antibody. Western Blot analysis of PLG expression in human liver. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

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