PLCB1 antibody

Principal name

PLCB1 antibody

Alternative names for PLCB1 antibody

Phospholipase C-I, PLC beta1, PLC-I, Phospholipase C-beta-1, PLC-beta-1, KIAA0581, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1, Phosphoinositide phospholipase C-beta-1

SwissProt ID

P10687 (Rat), P10894 (Bovin), Q9H8H5 (Human), Q9NQ66 (Human), Q9Z1B3 (Mouse)

Gene ID

23236 (PLCB1), 287026, 18795

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunoprecipitation (IP)

Background of PLCB1 antibody

Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. There are many mammalian PLC isozymes, including PLC beta1, PLC beta2, PLC beta3, PLC beta4, PLC gamma1, PLC gamma2, PLC delta1, PLC delta2 and PLC eta) with molecular weights ranging from 85 to 150 kDa. PLC beta1, one of the PLC beta isozymes, exists as two immunologically distinguishable proteins of 150 (PLC-beta1a) and 140 kDa (PLC beta1b). The two isoforms encode in two distinct transcripts and generated by alternative splicing of a single gene. PLC beta1a is preferentially expressed in the cytosol, whereas PLC beta1b is predominantly localized in the nuclei. PLC beta1 is a G-protein-dependent phosphodiesterase that hydrolyses phosphatidylinositol 4,5 biphosphate into inositol 1,4,5-triphosphate and diacylglycerol after the stimulation of a variety of neurotransmitter receptors at the cell surface.

General readings

Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Woodcock, E.A., et al. J. Mol. Cell. Cardiol. 47(5):676-683(2009)
Zhang, Y., et al. J. Recept. Signal Transduct. Res. 29(1):52-62(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLCB1 antibody

Western blot analysis of extracts of NCI-H460 cell lines, using PLCB1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PLCB1 (C-term) antibody

Human brain stained with Anti-PLC-beta1, cat# AP15734PU. Rabbit Purified Hu, Ms, Rt P
0.5 ml / €360.00
  Acris Antibodies GmbH

PLCB1 (C-term) antibody

Human brain stained with Anti-PLC-beta1, cat# AP15734PU. Rabbit Purified Hu, Ms, Rt P
1 ml / €520.00
  Acris Antibodies GmbH

PLCB1 (C-term) antibody

Human brain stained with Anti-PLC-beta1, cat# AP15734PU. Rabbit Purified Hu, Ms, Rt P
0.1 ml / €190.00
  Acris Antibodies GmbH

PLCB1 antibody

WB Suggested Anti-PLCB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that PLCB1 is expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PLCB1 antibody

Host: Rabbit; Target Name: Plcb1; Sample Tissue: Mouse Testis lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

PLCB1 (C-term) antibody

Western blot analysis of PLCB1 Antibody (C-term) Cat.-No AP53333PU-N in HL-60 cell line lysates (35ug/lane). PLCB1 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PLCB1 antibody

PLCB1 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

PLCB1 antibody

PLCB1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PLCB1 antibody

Immunohistochemical staining of PLCB1 on formalin fixed, paraffin embedded human brain with PLCB1 polyclonal antibody. Rabbit Hu P
0.1 ml / €390.00
  Abnova Taiwan Corp.

PLCB1 antibody

Human HepG2; WB Suggested Anti-PLCB1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate. There is BioGPS gene expression data showing that PLCB1 is expressed in HepG2.; PLCB1 antibody - middle region (ARP55844_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

PLCB1 antibody

PLCB1 Rabbit IgG Hu, Ms, Rt P
7 ml / €380.00
  Novus Biologicals Inc.

PLCB1 antibody

Western Blot: Phospholipase C beta 1 Antibody [NBP1-58257] - This Anti-PLCB1 antibody was used in Western Blot of HepG2     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PLCB1 (transcript variant 1)

PLCB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PLCB1 (transcript variant 2)

PLCB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PLCB1

PLCB1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PLCB1

PLCB1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PLCB1 overexpression lysate

PLCB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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