PLD6 antibody

Principal name

PLD6 antibody

Alternative names for PLD6 antibody

Phospholipase D6, PLD 6, Choline phosphatase 6, Phosphatidylcholine-hydrolyzing phospholipase D6

SwissProt ID

A1L1C2 (Xenla), Q5SWZ9 (Mouse), Q8N2A8 (Human)

Gene ID

201164 (PLD6)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of PLD6 antibody

PLD6 is a cardiolipin hydrolase present at the mitochondrial outer membrane required both for mitochondrial fusion and piR metabolic process. PLD6 acts by catalyzing the hydrolysis of cardiolipin (diphosphatidylglycerol) to form phosphatidate (phosphatidic acid or PA) at the mitochondrial outer membrane surface, promoting mitochondrial fusion. The production of phosphatidate also regulates the piR metabolic process by promoting recruitment and/or activation of components of the meiotic nuage, also med P granule, a critical step for primary biogenesis of piRs. It is required during spermatogenesis to repress transposable elements and prevent their mobilization via its role in the piR metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRs and Piwi proteins and govern the methylation and subsequent repression of transposons.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLD6 antibody

Host: Rabbit; Target Name: PLD6; Sample Tissue: Fetal Heart lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PLD6 (Center) antibody

Western blot analysis of PLD6 Antibody (Center) Cat.-No AP53346PU-N in mouse testis tissue lysates (35ug/lane). This demonstrates the PLD6 antibody detected the PLD6 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PLD6

PLD6 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

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