Plectin antibody

Principal name

Plectin antibody

Alternative names for Plectin antibody

PLEC, Plectin-1, PLEC1, PCN, PLTN, Hemidesmosomal protein 1

SwissProt ID

P30427 (Rat), Q15149 (Human), Q9QXR8 (Mouse), Q9QXS1 (Mouse)

Gene ID

5339 (PLEC)

Available reactivities

Fi (Fish), Hu (Human), Xen (Xenopus), Bov (Bovine), Ms (Mouse), Marsupials, Rt (Rat), Mam (Mammalia)

Available hosts

Guinea Pig, Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Plectin antibody

Plectin, a 500-kDa intermediate filament binding protein, is localized to the cytoplasm and acts to both stabilize and give strength to cells via cross-linking. Plectin cross-links intermediate filaments to microtubules and microfilaments, and anchors intermediate filaments to the plasma and nuclear membranes. Plectin binds many proteins, including actin, vimentin, and Lamin B. Phosphorylation by PKA or PKC results in decreased binding to Lamin B, and phosphorylation by PKA enhances the plectin-vimentin interactions.

General readings

General / background references:Foisner R et al. Monoclonal antibody mapping of structural and functional plectin epitopes. J Cell Biol 112:397-405 (1991). PubMed PMID: 1704007
Wiche G et al. Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical coiled coil. J Cell Biol 114:83-99 (1991). PubMed PMID: 2050743
Wiche G Plectin: general overview and appraisal of its potential role as a subunit protein of the cytomatrix. Crit Rev Biochem Mol Biol 24:41-67 (1989). PubMed PMID: 2667895

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Plectin antibody

Plectin Mouse IgG1 10F6 Purified Hu, Ms, Rt C, WB
50 µg / €350.00
  Acris Antibodies GmbH

Plectin (C-term) antibody

Plectin Guinea Pig Serum Fi, Hu, Xen C, ICC/IF, P, WB
0.1 ml / €350.00
  Acris Antibodies GmbH

Plectin (C-term) antibody

Plectin Guinea Pig Serum Bov, Fi, Hu, Ms, Xen C, ICC/IF, P, WB
0.1 ml / €350.00
  Acris Antibodies GmbH

Plectin antibody

Plectin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Plectin antibody

Detection limit for recombinant GST tagged PLEC1 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 4D12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Plectin antibody

Plectin Mouse IgG2a 4C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Plectin antibody

Plectin Mouse IgG1 7A8 Ascites Hu, Mam, Ms, Rt C, E, ICC/IF, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Plectin

Plectin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Plectin

Plectin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

9 Item(s)

per page
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