PLEKHM1 antibody

Principal name

PLEKHM1 antibody

Alternative names for PLEKHM1 antibody

KIAA0356, Pleckstrin homology domain-containing family M member 1, PH domain-containing family M member 1

SwissProt ID

Q5PQS0 (Rat), Q7TSI1 (Mouse), Q9Y4G2 (Human)

Gene ID

9842 (PLEKHM1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PLEKHM1 antibody

Involved in vesicular transport in the osteoclast (By similarity). May have a role in sialyl-lex-mediated transduction of apoptotic signals.Tissue specificity: Expressed in placenta, liver, prostate, thymus, spleen, ovary, colon, colon carcinoma and peripheral blood lymphocytes (PBL). Weakly expressed in brain, lung, kidney, and testis. No expression in heart, skeletal muscle, pancreas and small intestine. Predominantly expressed in the breast carcinoma cell line MCF-7.Involvement in disease:Defects in PLEKHM1 are the cause of osteopetrosis autosomal recessive type 6 (OPTB6); also known as autosomal recessive osteopetrosis intermediate form. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive form occurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood. Autosomal recessive osteopetrosis is usually associated with normal or elevated amount of non-functional osteoclasts.

General readings

Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109(2010)
Del Fattore, A., et al. J. Bone Miner. Res. 23(3):380-391(2008)
Van Wesenbeeck, L., et al. J. Clin. Invest. 117(4):919-930(2007)
Hartel-Schenk, S., et al. Glycoconj. J. 18 (11-12), 915-923 (2001)

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLEKHM1 antibody

Western blot analysis of PLEKHM1 in human lung tissue lysate with PLEKHM1 antibody at 1 µg/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PLEKHM1 Control Peptide

PLEKHM1
50 µg / €160.00
  Acris Antibodies GmbH

PLEKHM1 (N-term) antibody

Western blot analysis of PLEKHM1 Antibody (N-term) Cat.-No AP53352PU-N in K562 cell line lysates (35ug/lane). This demonstrates the PLEKHM1 antibody detected the PLEKHM1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PLEKHM1 antibody

Detection limit for recombinant GST tagged PLEKHM1 is approximately 1ng/ml as a capture antibody. Mouse IgG2b 1C9 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

PLEKHM1 antibody

Immunohistochemistry-Paraffin: PLEKHM1 Antibody [NBP1-77088] - Human lung tissue with PLEKHM1 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

PLEKHM1 antibody

Immunohistochemistry-Paraffin: PLEKHM1 Antibody [NBP1-83013] Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

PLEKHM1 antibody

Immunohistochemistry-Paraffin: PLEKHM1 Antibody [NBP1-83014] Immunohistochemical staining of human skin shows strong cytoplasmic positivity in basal epidermal cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PLEKHM1

PLEKHM1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PLEKHM1

PLEKHM1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PLEKHM1

PLEKHM1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PLEKHM1 overexpression lysate

PLEKHM1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

per page
  • LinkedIn