Plexin A1 antibody

Principal name

Plexin A1 antibody

Alternative names for Plexin A1 antibody

Plexin-A1, PLXNA1, NOV, PLXN1, Semaphorin receptor NOV

SwissProt ID

P70206 (Mouse), Q9UIW2 (Human)

Gene ID

5361 (PLXNA1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of Plexin A1 antibody

Plexins are a family of large integral membrane proteins that complex with neuropilins to form semaphorin co-receptors. The extracellular region of plexins contain a semaphorin domain, multiple glycine rich motifs, and MET related sequences. The cytoplasmic region contains a Sex/Plexin domain and putative tyrosine phosphorylation sites that mediate signal transduction after activation. This region in Plexin A1 binds the RhoGTPases, Rnd1 and RhoD. Recruitment of Rnd1 has been implicated in the cytoskeletal collapse that occurs after semaphorin mediated activation of Plexin A1, while RhoD may block this collapsing activity through interaction with the cytoplasmic region of Plexin A1. The expression of Plexin A1, along with the co receptor Neuropilin 1, is upregulated in neurons after central nervous system injury. The axons from these neurons cannot cross semaphorin 3A containing regions at the site of injury. Thus, semaphorin 3A and its co-receptors, Plexin A1 and Neuropilin 1, may have significant roles in axon regeneration after neuronal injury.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Plexin A1 antibody

Immunocytochemical labeling using PLXNA1 polyclonal antibody ( Cat # PAB7879 ) in COS-7 cells mock transfected (A) or transfected with Myc-tagged mouse PLXNA1 construct (B). The specificity of the binding in (B) was demonstrated by using PLXNA1 peptide in the presence of PLXNA1 polyclonal antibody ( Cat # PAB7879 ) (C). Rabbit Hu, Ms, Rt E, ICC/IF, IP, WB
0.1 ml / €400.00
  Abnova Taiwan Corp.

Plexin A1 antibody

Immunocytochemical labeling using PLXNA1 polyclonal antibody ( Cat # PAB7890 ) in COS-7 cells mock transfected (A) or transfected with Myc-tagged mouse PLXNA1 construct (B). The specificity of the binding in (B) was demonstrated by using PLXNA1 peptide in the presence of PLXNA1 polyclonal antibody ( Cat # PAB7890 ) (C). Rabbit Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €400.00
  Abnova Taiwan Corp.

Plexin A1 antibody

Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544] - Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544] Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Plexin A1

Plexin A1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PLXNA1 overexpression lysate

PLXNA1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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